April 2024 in “Medical & clinical research” This study reviews the range of both conventional and unconventional treatments for Alopecia Areata, highlighting the promise of biological therapies like JAK inhibitors, but notes more research is needed to optimize treatment effectiveness and personalization.
February 2024 in “International neuropsychiatric disease journal” In this abstract, the authors provide an overview of the psychological impact of alopecia areata, highlighting how this autoimmune disorder can lead to reduced quality of life, increased anxiety and depression symptoms, and decreased work productivity due to hair loss and its social implications.
June 2023 in “Dermatology and therapy” This literature review highlights challenges in managing alopecia areata in the Middle East and Africa, noting significant regional gaps in data, treatment guidelines, and public awareness that impede patient care and emphasize the need for improved support and resources.
January 2023 in “Integrative Journal of Medical Sciences” This report presents a case of a child with hypothyroidism and poorly controlled type 1 diabetes developing both Mauriac syndrome and Van Wyk–Grumbach syndrome, two rare complications.
January 2023 in “National journal of physiology, pharmacy and pharmacology” This study of South Indian patients with autoimmune rheumatic diseases using low-dose methotrexate reported that while mild adverse effects such as hair loss and nausea were common, serious events like cytopenia were less frequent, and folic acid supplementation significantly reduced their prevalence.
January 2023 in “Tehnika” This article discusses the challenges in diagnosing and treating autoimmune diseases, emphasizing the need for regenerative medicine approaches to address the root causes rather than just suppressing symptoms.
September 2022 in “Skin appendage disorders” This article explores potential risk factors for central centrifugal cicatricial alopecia and suggests that seborrheic dermatitis may play a role in its development, but it reports no new scientific findings.
March 2022 in “Women's health issues” This review highlights the urgent need for increased research and policy support for autoimmune and immune-mediated skin diseases, which are on the rise and disproportionately affect women's health in the United States, suggesting a focus on gender and socioenvironmental factors.
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This article reviews the National Alopecia Areata Foundation's biennial research summits, aimed at advancing treatment development for alopecia areata, and reports no new results.
November 2013 in “Dalhousie Medical Journal” This review discusses the epidemiology and cutaneous manifestations of lupus erythematosus, highlighting comparable incidence rates between cutaneous and systemic forms, but reports no new findings.
January 2012 in “Elsevier eBooks” This article discusses various forms of hair loss and their psychological impacts, noting the lack of definitive treatments, but reports no new clinical findings.
170 citations
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December 2009 in “Histopathology” This review discusses the histopathological diagnosis of scarring and non-scarring alopecias, emphasizing the importance of adequate tissue sampling and clinical information; it reports no new empirical results.
69 citations
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February 2008 in “The American journal of pathology” This study found that local injections of interleukin-4 and neutralizing anti-interferon-γ antibody effectively treated alopecia in a mouse model, suggesting potential therapeutic pathways for human alopecia areata.
67 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the causes, associated conditions, and treatment options for alopecia areata, such as corticosteroids and wigs, but reports no new clinical findings.
19 citations
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March 1997 in “Journal of Cutaneous Pathology” This study observed that patients with alopecia areata often have a T-cell receptor repertoire in skin lesions that suggests a specific antigen-driven immune response may be important in the disease's pathogenesis.
1 citations
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April 2025 in “Revista científica FACS.” This study explored the potential use of natural ingredients in managing alopecia areata, investigating their safety and efficacy as alternatives to conventional chemical treatments.
1 citations
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December 2017 in “Hygeia - Revista Brasileira de Geografia Médica e da Saúde” This study discusses potential connections between geography, stress, and alopecia areata, suggesting that stress is a key factor influencing the condition, alongside geographic factors.
June 2026 in “Revista Brasileira de Saúde” This study reviewed current scientific evidence on how scalp microbiome alterations may affect hair growth, citing connections to inflammatory and immune processes and suggesting potential for therapeutic targeting, though further studies are needed to confirm clinical applications.
December 2025 in “International Journal of Research in Ayurveda and Pharmacy” This case report details a 19-year-old female with autoimmune hair loss successfully managed using an integrated Ayurvedic approach, achieving complete hair regrowth and symptom resolution within two months, suggesting potential efficacy for autoimmune conditions warranting further study.
In this study, researchers found that CD4 T cells from the skin draining lymph nodes of mice with alopecia areata can transfer the disease to recipient mice, highlighting the key role of these cells and their interaction with CD8 T cells in the disease's development.
August 2023 in “International Ayurvedic medical journal” This case study describes the successful treatment of a 7-year-old girl with alopecia areata using Ayurvedic approaches targeting skin and autoimmune issues, suggesting a potential alternative to long-term oral corticosteroids, which can cause undesirable side effects.
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, 25% of CCHCR1-deficient mice exposed to stress developed hair loss similar to human alopecia areata, suggesting CCHCR1 is a susceptibility gene for the disease.
March 2015 in “Zagazig University Medical Journal” The study found that CK15 expression, representing hair follicle stem cell activity, was reduced or absent in scarred primary cicatricial alopecia lesions, suggesting stem cell damage may contribute to the scarring process.
January 1989 in “Clinical and Experimental Dermatology” This symposium abstract reports no new experimental results and discusses the pathophysiology of hair growth as presented at an event organized by the Institute of Dermatology.
102 citations
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December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.
2 citations
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December 2023 in “Journal of clinical immunology” This study describes the positive effects of the JAK inhibitor ruxolitinib in treating autoimmune manifestations in three patients with autoimmune polyendocrine syndrome type-1 over a period of at least 30 months, with excellent tolerance and no adverse events observed.
May 2026 in “International Journal of Homoeopathic Sciences” This study found that individualized homeopathic medicine can significantly improve outcomes in patients with alopecia areata, including complete hair regrowth and reduced SALT scores within 5 to 12 months, without relapse, and shows promise for alopecia universalis through targeted miasmatic and constitutional remedies.
May 2025 in “Journal of Diverse Medical Research Medicosphere” This article reports a rare case of angioedema in a pregnant woman with systemic lupus erythematosus, highlighting a need for further research in this area.
July 2019 in “Dermatology practical & conceptual” This report presents personal observations of alopecia areata in twins with autoimmune thyroiditis and suggests a possible link, though it does not provide new clinical results.
151 citations
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February 2007 in “International Journal of Dermatology” This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.