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      A Case of Vitiligo Combined With Systemic Lupus Erythematosus Treated With Tofacitinib

      research A Case of Vitiligo Combined with Systemic Lupus Erythematosus Treated with Tofacitinib

      March 2024 in “Clinical, cosmetic and investigational dermatology”
      In this report, a patient with vitiligo and systemic lupus erythematosus achieved complete skin repigmentation after 30 days of treatment with the oral JAK inhibitor tofacitinib, with no adverse reactions, suggesting its efficacy and safety as a potential treatment for vitiligo with coexisting autoimmune conditions.
      Alopecia Areata: A Review of Disease Pathogenesis

      research Alopecia areata: a review of disease pathogenesis

      191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
      This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
      Biology and Genetics of Hair

      research Biology and Genetics of Hair

      89 citations , September 2010 in “Annual Review of Genomics and Human Genetics”
      This review discusses the genetic factors involved in hair follicle morphogenesis and cycling and reports no new clinical results; it emphasizes the role of genes in hereditary hair diseases.
      Psychophysiological Mechanisms of Stress Impact on Hair Loss Processes

      research Psychophysiological Mechanisms of Stress Impact on Hair Loss Processes

      September 2025 in “International Journal of Science and Research (IJSR)”
      This theoretical review analyzes how stress affects hair loss through hormonal and neural pathways, indicating that knowledgeable hairdressers could help in early detection and guide clients toward medical interventions, highlighting a potential collaboration between aesthetic care and medical treatment for stress-induced alopecia.
      A Case of Alopecia Areata After Rabies Vaccination: Unreported Adverse Effect?

      research A case of alopecia areata after rabies vaccination: unreported adverse effect?

      January 2024 in “Clinical and Experimental Vaccine Research”
      In this report, the authors describe a case where a child developed alopecia areata after receiving the fifth dose of a rabies vaccine, suggesting that the vaccine may predispose to this autoimmune hair loss by affecting immune regulation.
      Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      1533 citations , October 2008 in “Endocrine reviews”
      This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
      Alopecia Areata: An Autoimmune Disease Causing Hair Loss

      research Alopecia Areata

      421 citations , April 2012 in “The New England Journal of Medicine”
      Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
      Alopecia Areata Update

      research Alopecia areata update

      391 citations , January 2010 in “Journal of The American Academy of Dermatology”
      This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.
      Skin Wound Healing in Humans and Mice: Challenges in Translational Research

      research Skin wound healing in humans and mice: Challenges in translational research

      276 citations , December 2017 in “Journal of Dermatological Science”
      This review discusses the limitations of animal models, particularly mice, in accurately predicting human skin wound healing outcomes and emphasizes understanding species-specific differences in skin characteristics for better translation to clinical settings.
      Signaling Involved in Hair Follicle Morphogenesis and Development

      research Signaling Involved in Hair Follicle Morphogenesis and Development

      223 citations , January 2014 in “International Journal of Molecular Sciences”
      This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.
      Alopecia Areata: Overview and Treatment Options

      research Alopecia areata

      151 citations , February 2007 in “International Journal of Dermatology”
      This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.
      Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management

      research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management

      102 citations , December 2017 in “˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings”
      This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.
      Human αβ and γδ T Cells in Skin Immunity and Disease

      research Human αβ and γδ T Cells in Skin Immunity and Disease

      83 citations , June 2018 in “Frontiers in immunology”
      This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.
      What Causes Hidradenitis Suppurativa?—15 Years After

      research What causes hidradenitis suppurativa ?—15 years after

      78 citations , October 2020 in “Experimental Dermatology”
      This review summarizes 15 years of clinical and experimental research advancements in hidradenitis suppurativa, highlighting its recognition as a uniquely healable inflammatory skin disease but reports no new clinical results.
      Clinical and Biological Impact of the Exposome on the Skin

      research Clinical and biological impact of the exposome on the skin

      77 citations , July 2020 in “Journal of the European Academy of Dermatology and Venereology”
      This review examines the skin exposome, including solar exposure, air pollution, hormones, nutrition, and psychological factors, but reports no new clinical results.

      research The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

      71 citations , May 2024 in “New England Journal of Medicine”
      This study investigated the impact of the JAK inhibitor ruxolitinib on APS-1 patients, reporting that treatment decreased excessive T-cell-derived interferon-γ, normalized inflammatory markers, and led to remission of several autoimmune symptoms without serious adverse effects.
      Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease

      research Local heroes or villains: tissue-resident memory T cells in human health and disease

      67 citations , January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology”
      This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.

      research Hair follicle is a target of stress hormone and autoimmune reactions

      61 citations , September 2010 in “Journal of Dermatological Science”
      This review discusses the interplay between hormonal and immune systems in hair follicles and reports no new results, highlighting the need for further research on their role in skin biology and alopecia areata.
      Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

      research Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

      47 citations , December 2019 in “Frontiers in immunology”
      This study identified a novel G207E STING mutation associated with severe inflammatory symptoms and suggested that common polymorphisms in TMEM173 and IFIH1 may modify the phenotype in affected individuals.