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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Different types of skin cells play specific roles in development, healing, and cancer.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Androgens can both increase and decrease hair growth in different parts of the body.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Hair loss needs more research for better treatments.

Some medicinal plants can help heal wounds and may lead to new treatments.

High androgen levels in young women with PCOS are linked to higher blood pressure.

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.