March 2021 in “Research Square (Research Square)” This study found that patients with RASopathies demonstrated lower levels of serum IgA and CD8 T cells compared to controls, potentially indicating an increased risk of developing autoimmune disorders.
March 2026 in “Frontiers in Medicine” This study provides a framework for understanding different types of alopecias based on immune privilege collapse at specific follicular sites, revealing distinct patterns in immune effector programs and stromal influences depending on the alopecia type.
17 citations
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August 2019 in “Frontiers in Immunology” This review examines non-invasive methods for diagnosing inflammatory skin diseases like lupus erythematosus and psoriatic inflammation using samples from plucked hair and skin tape-strips, but no new clinical results are presented.
1 citations
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February 2021 in “Farmacja Polska” This article reviews the role of the JAK-STAT pathway in inflammatory skin diseases and considers the therapeutic benefits of JAK inhibitors, presenting them as promising treatments but reports no new experimental results.
May 2025 in “The Journal of Rheumatology” In this case report, two patients with polyautoimmunity and difficult-to-treat lupus erythematosus experienced significant symptom improvement after adding anifrolumab to their regimen, suggesting its potential as an effective add-on therapy for refractory cutaneous symptoms in autoimmune conditions characterized by elevated interferon alpha activity.
2 citations
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July 2022 in “Cureus” This case report describes a rare patient with Sjogren's syndrome who experienced recurrent pneumothorax, resolved through surgical intervention, highlighting pneumothorax as an unusual complication of the condition.
November 2025 in “Frontiers in Immunology” This study introduces stem cell activity as a key factor influencing the effects of IFN-γ and TGF-β1 on autoimmune disease dynamics, showing that varying cytokine levels can modulate stem cell activity and immune privilege, impacting tissue regeneration and disease flares.
May 2015 in “Journal of the American Academy of Dermatology” Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This study aims to evaluate the effectiveness of platelet-rich plasma as a sole treatment for alopecia areata, but it reports no new results.
1 citations
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August 2018 in “Journal of the American Academy of Dermatology”
June 2023 in “Benha Journal of Applied Sciences” This review concluded that interleukin-17 is involved in the development of female-pattern baldness, suggesting a potential inflammatory role in the condition’s underlying causes.
January 2017 in “Archives of clinical and biomedical research” This case report suggests that melanin, as an energy generator, may offer a new perspective on studying and treating autoimmune disorders such as alopecia areata.
February 2024 in “International neuropsychiatric disease journal” In this abstract, the authors provide an overview of the psychological impact of alopecia areata, highlighting how this autoimmune disorder can lead to reduced quality of life, increased anxiety and depression symptoms, and decreased work productivity due to hair loss and its social implications.
This review highlights new treatment options for alopecia, including JAK inhibitors and Wnt pathway-targeting therapies, which may offer better efficacy and safety than traditional treatments like minoxidil and finasteride, but notes the need for more research on long-term effects and patient-specific responses.
December 2023 in “EPRA international journal of multidisciplinary research” In this review, researchers examined current knowledge on alopecia areata, finding it affects approximately 2% of individuals, with a likely autoimmune and genetic basis, and highlighting its association with other medical and psychiatric conditions, although no cure currently exists.
January 2026 in “International Journal of All Research Education & Scientific Methods” This review highlights recent advancements in understanding and treating alopecia, emphasizing genetic and immune factors involved in different forms, and discusses emerging therapies such as gene-editing and exosome-based treatments, though achieving complete hair regrowth remains a challenge.
3 citations
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June 2006 in “Expert Review of Dermatology” This review discusses recent advances in hair follicle research, highlighting therapeutic and cosmetic applications, but reports no new study results.
November 2022 in “CARDIOMETRY” This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.
September 2017 in “Current Issues in Pharmacy and Medical Sciences” This review discusses the use of mesenchymal stem cells in treating diseases, particularly focusing on their application in pediatric Graft-versus-Host Disease, with most studies reporting safety and effectiveness in animals.
1 citations
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September 2023 in “Journal of drugs in dermatology” This article discusses the perspectives of clinicians and patients on alopecia areata, an autoimmune disorder with significant psychosocial impacts, highlighting the unpredictability and limited effectiveness of current treatments as well as the key unmet needs and gaps in care.
1 citations
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September 2021 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that female patients with alopecia areata, especially those with nail abnormalities and atopic diseases, have a higher prevalence of autoimmune disease comorbidities.
January 2014 in “IOSR journal of pharmacy” This case report identifies alopecia universalis as a probable adverse drug reaction to adalimumab in a patient with psoriasis and psoriatic arthritis.
January 2026 in “International Research Journal of Modernization in Engineering Technology and Science” This review outlines the existing understanding of alopecia areata, detailing its autoimmune nature, clinical presentation, histology, and management strategies, with corticosteroids highlighted as the most popular treatment option.
January 2026 in “International Journal of Research and Innovation in Applied Science” This article discusses the similarities between alopecia areata and Indralupta in Ayurveda and reports no new clinical results, highlighting traditional and modern management approaches for the condition.
January 2025 in “International Journal of Homoeopathic Sciences” This article discusses individualized homeopathy for treating alopecia areata and reports promising results, suggesting potential effectiveness; however, it highlights the unpredictability of hair follicle remission with conventional treatments.
October 2022 in “JAAD international” This study found that more than 70% of patients with autoimmune blistering diseases experienced alopecia, with about 10% having scarring alopecia, and elevated Dsg1 ratios were linked to hair loss in pemphigus vulgaris.
144 citations
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July 2002 in “Clinical and Experimental Dermatology” This article reviews the concept of telogen effluvium and emphasizes the importance of identifying triggers and using diagnostic investigations to determine the cause of hair loss, without reporting new results.
23 citations
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November 2024 in “Scientific Reports” In this study, researchers found that Hashimoto's thyroiditis patients, despite being in euthyroid status, experienced more severe extrathyroidal symptoms compared to healthy controls, and elevated thyroid antibodies were linked to lower health-related quality of life and increased inflammation.
13 citations
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November 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that topical clobetasol propionate cream provided a modest improvement in hair regrowth for alopecia areata patients, though those with atopy had higher relapse rates after treatment completion.
August 2024 in “Clinical and Medical Engineering Live” This literature review examines the complexities of childhood alopecia areata, focusing on its forms, gene expression, and causes, providing a comprehensive analysis of this autoimmune disorder.