April 2016 in “Journal of the American Academy of Dermatology” Treatment improved some symptoms but not all.
717 citations,
June 2010 in “Nature” Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
98 citations,
March 2019 in “Frontiers in immunology” Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
5 citations,
March 2023 in “Journal of the American Academy of Dermatology” Prurigo pigmentosa mainly affects middle-aged White and Asian women, often linked to a ketogenic diet, and is best treated with oral antibiotics.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
11 citations,
September 2021 in “Anais Brasileiros de Dermatologia” The conclusion is that early diagnosis of skin signs linked to diseases like Lupus, Dermatomyositis, and Rheumatoid Arthritis is crucial to prevent serious complications.
January 2025 in “International Journal of Molecular Sciences” Psoriasis involves immune and genetic factors, and understanding these can improve treatments.
August 2024 in “EMJ Dermatology” Non-scarring alopecia in females affects emotional well-being and requires accurate diagnosis and personalized treatment.
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” The document concludes that various skin conditions have specific characteristics and treatments, and highlights the importance of vitamin D in managing these dermatological issues.
31 citations,
January 2009 in “Autoimmunity Reviews” Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
1 citations,
September 2016 in “Veterinary dermatology” A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
April 2023 in “Indian journal of paediatric dermatology” Early diagnosis and treatment of nail lichen planus in children can prevent permanent nail damage.
1 citations,
January 2018 in “Skin appendage disorders” The complement system might be involved in the development of alopecia areata and could lead to new treatments.
January 2024 in “Pan African Medical Journal” Non-scarring hair loss is common in lupus patients and can be diagnosed with specific hair and tissue tests.
26 citations,
March 2007 in “Clinical and experimental dermatology” Pimecrolimus cream is not effective for treating alopecia areata.
May 2015 in “Journal of the American Academy of Dermatology” Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.
21 citations,
January 2013 in “Annals of dermatology/Annals of Dermatology” The combination of cyclosporine and PUVA might help treat severe alopecia areata.
10 citations,
July 2008 in “Journal of Cutaneous Pathology” Increased mucin in the skin might indicate lupus in patients with hair loss, but more research is needed.
October 2020 in “Veterinary Dermatology” New treatments and diagnostic methods for various animal skin conditions showed promising results.
January 2012 in “Springer eBooks” Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.
62 citations,
June 2015 in “The Journal of Dermatology” People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.
36 citations,
May 2011 in “Dermatologic therapy” No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.
25 citations,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
22 citations,
June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
20 citations,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
18 citations,
March 2004 in “Clinics in Dermatology” Lupus can cause hair loss and nail changes, with treatments available for both.
17 citations,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.