research Does Mitochondrial Dysfunction Drive Immune Privilege Collapse in Lichen Planopilaris Pathogenesis?
Mitochondrial dysfunction may contribute to chronic inflammation and immune system issues in Lichen planopilaris.
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research Alopecia Areata: An Overview of Treatments and Efficacy
No treatment alters the natural progression of alopecia areata, and effectiveness varies, with some possibly working better in children.
research Graft Versus Host Disease-Like: A New Paraneoplastic Syndrome
A woman with thymoma developed a rare chronic condition similar to graft versus host disease after surgery.
research Wound Healing
Fine hairs improve male pattern baldness treatment, alopecia areata causes remain unknown, and hair can recover from dye damage over time.
research Generalized Vitiligo Associated Autoimmune Diseases in Japanese Patients and Their Families
Japanese vitiligo patients and their families often have other autoimmune diseases.
research The Analysis of Genetics and Associated Autoimmune Diseases in Chinese Vitiligo Patients
Generalized vitiligo in Chinese patients is linked to other autoimmune diseases, especially in familial cases.
research Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance
Thyroid function affects skin health, with a complex interaction between the two.
research Lichen Planopilaris: Retrospective Study on the Characteristics and Treatment of 291 Patients
Women are more likely to have Lichen planopilaris, and treatments with cyclosporine and methotrexate are most effective but less safe than mycophenolate mofetil.
research Gender Aspects in Skin Diseases
Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
research Autoimmune Polyendocrine Syndrome Type 1: An Italian Survey on 158 Patients
APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
research New Aspects of the Treatment of Alopecia Areata
Personalized treatment plans are important for people with alopecia areata.
research Medical Dermatologic Conditions in Transgender Women
Hormone therapy in transgender women can affect hair growth and acne, and there are specific skin issues related to gender-affirming surgery, but more research is needed on their dermatological health.
research Epidemiology, Management, and the Associated Burden of Mental Health Illness, Atopic and Autoimmune Conditions, and Common Infections in Alopecia Areata: Protocol for an Observational Study Series
People with alopecia areata have higher rates of mental health issues, autoimmune diseases, and infections.
research The Possible Implication of the S250C Variant of the Autoimmune Regulator Protein in a Patient with Autoimmunity and Immunodeficiency: In Silico Analysis Suggests a Molecular Pathogenic Mechanism for the Variant
The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
research Polyglandular Autoimmune Syndrome Type III with a Prevalence of Cutaneous Features
PAS III can cause multiple autoimmune diseases with noticeable skin issues.
research Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Syndrome (APECED) Due to AIRE T16M Mutation in a Consanguineous Greek Girl
An 11-year-old Greek girl was diagnosed with a rare genetic disorder, highlighting the importance of genetic testing and family history.
research Immunologic Studies in Patients With Alopecia Areata
Alopecia areata may be caused by the immune system attacking hair follicles.
research Pruritus, Allergy and Autoimmunity: Paving the Way for an Integrated Understanding of Psychodermatological Diseases
The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.
research Retrospective Analysis of the Application of Fumaric Acid Esters in 13 Patients with Alopecia Areata
Fumaric acid esters might help treat alopecia areata, but more research is needed.
research Lupus Erythematosus Tumidus with Autoimmune Thyroid Dysfunction as the First Presentation of Systemic Lupus Erythematosus: A Case Report and Review of the Literature
Recognizing LET and AITD can help diagnose SLE early for better treatment.
research Hypoparathyroidism as the Single Major Component for Decades of Autoimmune Polyglandular Syndrome Type 1
A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.
research Latent Polyglandular Autoimmune Syndrome Type 2 Case Diagnosed During a Shock Manifestation
A hidden autoimmune syndrome was found during a shock, showing thyroid, adrenal, and ovarian issues.
research A Case of Hemi-Isaac's Syndrome
A man with Isaac's syndrome affecting only one side of his body improved after immune system-targeted treatment.
research Systemic Lupus Erythematosus in Men
Men with systemic lupus erythematosus often have more severe symptoms but can respond well to treatment.
research Steroid Responsive Mononeuritis Multiplex in the Cronkhite-Canada Syndrome
Steroid treatment improved both gut and nerve symptoms in a man with Cronkhite–Canada syndrome.
research Efficacy of Baricitinib Compared to Conventional Therapy for Alopecia Areata
Baricitinib is effective for Alopecia Areata but requires careful patient history evaluation.
research Insights Into Alopecia Areata: A Systematic Review Of Prevalence, Pathogenesis, And Psychological Consequences
Alopecia Areata affects people of all ages worldwide, is likely caused by genetic and environmental factors, and can lead to stress and depression, highlighting the need for treatments that address both physical and mental health.
research Tofacitinib Treatment in a Severe Pediatric Alopecia Areata: A Case Report and a Literature Review
Oral tofacitinib may be an effective future treatment for children with severe alopecia areata, but more research is needed.