426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
400 citations,
January 2014 in “British Journal of Sports Medicine” The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.
365 citations,
November 2018 in “Journal of Allergy and Clinical Immunology” People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
276 citations,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.
224 citations,
February 2013 in “The Journal of clinical investigation/The journal of clinical investigation” ERG increases SOX9, promoting prostate cancer growth and invasion.
219 citations,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
214 citations,
September 2015 in “Stem Cells Translational Medicine” Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
182 citations,
November 2018 in “Cosmetics” Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
169 citations,
February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
163 citations,
October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
154 citations,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
148 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
102 citations,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
94 citations,
July 2003 in “Journal of biological chemistry/The Journal of biological chemistry” EGF controls hair growth by regulating hair follicles' growth phases.
79 citations,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
59 citations,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
53 citations,
July 2016 in “Cosmetics” Future hair cosmetics will be safer and more effective.
45 citations,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
45 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Understanding hair follicles through various models can help develop new treatments for hair disorders.
43 citations,
January 2016 in “Oxidative medicine and cellular longevity” THSG from a Chinese plant helps with aging and related diseases.
40 citations,
November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
36 citations,
August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
36 citations,
February 2016 in “British journal of pharmacology” Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
35 citations,
January 2017 in “Journal of Dermatological Science” Stress can cause early aging in certain skin cells, leading to problems with hair growth.
30 citations,
October 2020 in “Frontiers in Plant Science” Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.
29 citations,
January 2020 in “Frontiers in endocrinology” Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
24 citations,
August 2020 in “JAMA dermatology” Persistent radiation-induced hair loss is dose-dependent, and treatments like topical minoxidil can be effective.