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The researchers reported that topical application of small-molecule Wnt inhibitors significantly reduced fibrosis and promoted regenerative wound healing in mice.

This study suggests that basonuclin may act as a tissue-specific transcription factor for ribosomal RNA genes by interacting with the promoter region necessary for high transcription levels in human keratinocytes.

This article describes a case of multiple perifollicular fibromas and suggests that cases previously reported as such might actually be instances of Birt‐Hogg‐Dubé syndrome.

This review highlights the potential for clinicians to recognize skin manifestations as a straightforward method to detect insulin resistance and improve management of diabetes and obesity.

In this study, researchers observed that 90% of patients with PCOS had cutaneous manifestations, with acne most common, and found associations between these skin conditions and high insulin or testosterone levels.

This review highlights the role of dermatologists in detecting early cutaneous signs of obesity-related metabolic syndrome, which may enable earlier treatment to prevent long-term consequences; it reports no new clinical results.

This clinical report describes a method for using tattoo marks to help align a facial prosthesis for a patient with skin flap reconstruction.

This review discusses the role of Janus-kinase inhibitors in treating severe atopic dermatitis and alopecia areata, presenting case studies that show their efficacy and calling for further research on long-term effectiveness and safety.

This study found that obese patients had higher prevalence and severity of skin conditions like acanthosis nigricans and infections compared to those with normal BMI, which could help detect metabolic syndrome early.

Using cheek skin and cartilage grafts for nose reconstruction after skin cancer surgery can maintain shape and function but may require multiple surgeries and hair removal in men.

In this study, JAK inhibitors for treating alopecia areata and atopic dermatitis were generally well tolerated in a real-world setting, with most adverse events being mild or moderate and rare serious cases resembling the general population incidence.

In this review, the authors discussed the clinical presentations and management of feline immune-mediated skin diseases such as erythema multiforme and Stevens-Johnson syndrome, noting that although these conditions are rare, they can severely affect cats' quality of life.

This review summarized the latest knowledge suggesting that Janus kinase inhibitors may have therapeutic potential for treating skin diseases like atopic dermatitis and psoriasis, especially when conventional therapies do not work.

In this source, it is highlighted that dermatologists can identify and manage eating disorders early, potentially improving outcomes and reducing irreversible damage from malnutrition, though specific results are not reported.

In this study, hirsutism was the most prevalent skin manifestation among women with PCOS, and a significant association was observed between certain skin changes and hormonal abnormalities such as insulin resistance and elevated prolactin levels.

This study found that infections were the most common skin issues in diabetics, especially among those with poorly controlled blood sugar.

In this study, common skin conditions in the geriatric population of Kerala were found to be widely prevalent, with significant associations between xanthelasma palpebrarum and dyslipidemia, and between cherry angioma and diabetes.

This review highlights the potential for JAK inhibitors to effectively treat inflammatory and autoimmune skin diseases by targeting the JAK-STAT signaling pathway, advocating for an integrated approach to enhance targeted therapy.

This review discusses the role of JAK inhibitors in treating atopic dermatitis, alopecia areata, and vitiligo, highlighting their effectiveness and safety considerations but stressing the need for further research on long-term safety and patient selection.

In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.

This study found that skin changes in morbidly obese individuals are associated with underlying metabolic disturbances but are not currently valuable as independent tools for assessing metabolic risk or treatment response.

This review found that oral JAK inhibitors, used off-label in various inflammatory skin disorders, often resulted in rapid and sustained clinical improvements with acceptable safety over several months, although the evidence is drawn from case-based reports.

This case report details the development of a psoriasiform rash and inflammatory alopecia in a 29-year-old man with severe atopic dermatitis following dupilumab treatment. The authors observed hair regrowth and eczema control after discontinuing dupilumab and beginning treatment with abrocitinib.

This study found that the JAK1 inhibitors baricitinib and abrocitinib significantly reduced mechanical alloknesis in a murine model of atopic dermatitis, whereas the JAK2 inhibitor AZ960 had no effect.

This study observed that among patients with PCOS, hirsutism was present in 75.63%, acne in 65%, and other skin conditions such as female pattern hair loss, acanthosis nigricans, and seborrhea in varying proportions, highlighting the dermatological impact of PCOS on patients' quality of life.

This study reviewed literature and assessed clinical data on treating alopecia areata linked with atopic diseases, finding that therapies like dupilumab, phototherapy, and JAK inhibitors may address overlapping symptoms, suggesting a focus on reducing pharmacological burden and enhancing quality of life.

This literature review found that Janus kinase inhibitors may help achieve remission in patients with refractory primary neutrophilic cicatricial alopecias, though data is limited to small case series and reports.

This review article highlights that obesity is a significant risk factor for several inflammatory skin conditions, such as psoriasis and atopic eczema, contributing to increased overall morbidity among those affected.

This study reported that the Pamona indigenous community near Lake Poso, Indonesia, relies on 21 macrofungi species for diverse uses, including food and medicine, helping to address malnutrition and disease prevention.

In this 2-year prospective study, researchers observed that weight loss through bariatric surgery in patients with morbid obesity led to improvements in various skin conditions, although it also resulted in hair loss (telogen effluvium) for over half of the participants.