April 2025 in “Materials Today Bio” In this study, researchers demonstrated that self-assembled gold nanoclusters with aptamers effectively deliver anti-NFκB aptamer drugs to inhibit hair follicle regeneration while being non-toxic to normal cells, offering a targeted treatment for hypertrichosis.
2 citations
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June 2025 in “Nano Research” This review discusses recent advancements in the assembly and potential applications of gold nanoclusters, but presents no new experimental results; the authors highlight the need for further exploration in this area.
29 citations
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November 2015 in “Acta Biomaterialia” This study found that water-filtered infrared A radiation can induce the release of a model drug from gold nanoparticle-doped particles in hair follicles in an ex vivo porcine skin model, suggesting feasibility for follicular drug delivery systems.
21 citations
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November 2020 in “Chemical Engineering Journal” In this study, an injectable hydrogel incorporating antibacterial agents was shown to effectively heal wounds and promote hair follicle and capillary regeneration, offering a promising approach for skin tissue engineering.
April 2026 in “Biomedical Materials” In this study, gold nanoparticle-conjugated curcumin and thymoquinone formulations were more effective against melanoma cells in 3D bioprinted scaffolds than free or co-administered phytochemicals, sustaining stress responses and overcoming tumor adaptation barriers.
August 2024 in “Journal of Controlled Release” In a study using an AGA mouse model, researchers observed that a novel topical gel combining hybrid extracellular vesicles, gold nanoparticles, and finasteride accelerated hair regrowth and improved hair quality more effectively than conventional minoxidil treatment, presenting a promising option with fewer side effects.
19 citations
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October 2021 in “Nano letters” In an animal study, this research explored the use of a self-therapeutic nanoparticle for treating psoriasis in mice, finding that it could prevent and treat psoriatic symptoms as effectively as standard therapies without causing side effects like hair loss and skin wrinkling.
January 2026 in “Microchemical Journal” In this study, researchers developed an electrochemical method using gold nanostructures on a glassy carbon electrode to detect minoxidil levels in hair lotions, and found it effectively quantified minoxidil in commercial products, revealing discrepancies in their labeled versus actual concentrations.
17 citations
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November 2024 in “Talanta” A new method was developed to detect pesticide residues on apples without damage.
37 citations
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August 2020 in “BMC Genomics” This study found that while genetic variants contribute minimally to predicting hair greying in a Polish population, age remains the primary predictor, underscoring the complexity of hair greying as a genetic trait.
September 2002 in “Fertility and sterility” This study found that hirsutism is more frequent among female relatives of PCOS patients, suggesting a hereditary aspect of PCOS, while premature balding was not more common among male relatives.
This study identified pectin in early immature durian fruits and found that pectin-oligosaccharides derived from them show stronger antioxidant and antiglycation activities, with potential applications in cosmetic products.
39 citations
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July 2013 in “Journal of dermatological science” This study found that microRNA levels in hair shafts were significantly decreased in scleroderma patients compared to normal subjects, suggesting they may serve as effective biomarkers.
37 citations
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July 2005 in “Journal of The American Academy of Dermatology” This article reviews the clinicopathologic features of short anagen syndrome in a child and suggests diagnostic methods like clinical examination and scalp hair growth rate measurement, without reporting new clinical results.
30 citations
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January 2019 in “Clinical Endocrinology” This study observed that serum AMH concentration and LH/FSH ratio showed comparable diagnostic value for PCOS among infertile women, though neither is adequate alone for diagnosis.
16 citations
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October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
13 citations
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September 2017 in “Skin appendage disorders” Some women with Frontal Fibrosing Alopecia also have Lichen Planopilaris, which can lead to more symptoms and affect hair outside the scalp.
8 citations
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January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study reports a novel TRbeta gene mutation associated with resistance to thyroid hormone syndrome, which may contribute to various forms of alopecia in the affected family members.
1 citations
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November 1987 in “Journal of The American Academy of Dermatology” Isotretinoin can raise CPK levels, so patients need monitoring, especially before surgery.
January 2024 in “Journal of surgical case reports” In this case study, researchers reported a 61-year-old postmenopausal woman with virilizing symptoms like hirsutism and voice deepening was found to have an androgen-secreting adrenal tumor, emphasizing the importance of considering this diagnosis in similar cases.
February 2018 in “BMJ case reports” This case report describes an 18-year-old woman with a pruritic rash featuring extensive confluent scaly erythema, hyperkeratotic follicular plugging, and waxy keratoderma on palms and soles.
May 2017 in “Journal of the American Academy of Dermatology” Graves' disease can cause hair loss in children and should be considered when treating pediatric alopecia areata.
67 citations
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January 2022 in “Theranostics” This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.
4 citations
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July 2025 in “International Journal of Nanomedicine” This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.
1 citations
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April 2026 in “Cancer Nanotechnology” This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.
356 citations
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September 2014 in “Journal of Clinical Research in Pediatric Endocrinology” This article discusses the rising prevalence and serious implications of childhood obesity and reports no new experimental findings; the authors emphasize the importance of prevention and early intervention through comprehensive management programs.
295 citations
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May 2016 in “Journal of the American Academy of Dermatology” This review examines the immunological aspects of alopecia areata, focusing on genetic, neuroimmunological, and immune privilege factors, but does not report new clinical findings.
151 citations
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November 2018 in “International Journal of Pharmaceutics” This review discusses various nanoparticles and nanoemulsions being investigated for transdermal drug delivery and reports no clinical results; it highlights potential applications in treating alopecia, wound healing, psoriasis, and melanoma.
112 citations
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November 2023 in “Nano-Micro Letters” This review discusses the developments over the past five years in nanozyme-based theranostics for tumor therapy, including their classification, design, and synergistic strategies. It also outlines the challenges and prospects of using nanozymes to enhance selectivity, biosafety, repeatability, and stability in therapeutic applications.
112 citations
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May 2019 in “Pharmacological Research” This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.