21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” This review discusses the research and development of vesicular carriers to enhance the delivery and effectiveness of active ingredients in cosmetic products, reporting no new clinical results.
21 citations
,
August 2016 in “Translational Andrology and Urology” This review discusses the pathophysiology of delayed ejaculation, highlighting the role of various biogenic and psychogenic factors, but reports no new clinical findings.
21 citations
,
April 2010 in “Veterinary Dermatology” This study documented the progression of exfoliative cutaneous lupus erythematosus in German shorthaired pointers and found generally poor responses to therapies, including immunomodulatory drugs and a TNF-α inhibitor.
21 citations
,
April 1982 in “Genetics Research” In this study, researchers observed that mice with the naked gene showed frequent absence of hair cuticle and cortical cells during follicle growth, with abnormal keratin deposition also noted.
20 citations
,
November 2019 in “Stem Cells” This study found that deleting the Hes1 gene disrupts hair regeneration by delaying anagen initiation and shortening the anagen phase, suggesting it's crucial for maintaining hair cycle homeostasis.
20 citations
,
December 2016 in “Neurodegenerative disease management” This study found that teriflunomide, an oral medication taken once daily, significantly slowed disability progression in patients with relapsing multiple sclerosis, supported by positive results in two Phase III trials and supplemented by various analyses including long-term studies and patient-reported outcomes.
20 citations
,
January 2015 in “Current problems in dermatology” This paper reviews recent research on hair graying, suggesting that an imbalance in oxidative stress handling may affect melanocyte stem cells and melanin production with age, and calls for exploring strategies to prolong melanin production.
20 citations
,
September 2005 in “Clinics in Dermatology” This review discusses the skin manifestations of metabolic diseases like diabetes and gout, emphasizing their role in diagnosis and monitoring, but it presents no new research findings.
20 citations
,
September 1978 in “International Journal of Dermatology” Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
19 citations
,
October 2017 in “The FASEB Journal” This study established an androgen-responsive human organ culture model using hair follicles, demonstrating that women's intermediate facial follicles grow more hair in response to men's higher androgen levels.
19 citations
,
November 2016 in “Dermatology and therapy” This study describes a case where stopping infliximab and using oral minocycline with topical treatments effectively resolved alopecia and scalp psoriasis in a woman with Crohn's disease.
19 citations
,
October 2013 in “Headache: The Journal of Head and Face Pain” This review discusses conventional and alternative treatments for trigeminal autonomic cephalalgias, including cluster headache, paroxysmal hemicrania, and SUNCT, and recommends specific medications without reporting new clinical findings.
19 citations
,
November 2012 in “British Journal of Dermatology” This study found that dopamine directly induces the catagen phase in human scalp hair follicles in vitro.
19 citations
,
March 2011 in “Cutaneous and Ocular Toxicology” Some chemicals absorbed through the skin can cause serious health problems.
19 citations
,
October 1994 in “Tumori Journal” This review discusses the current medical treatments for hepatocellular carcinoma, noting that while new local therapies show high response rates, their true impact on patient survival is uncertain.
18 citations
,
September 2023 in “Nutrition Research Reviews” In this scoping review, researchers found that while some dietary approaches may help improve psoriasis symptoms—particularly in those with obesity or coeliac disease—the overall evidence is limited, and larger studies are necessary to identify effective diets for the broader psoriasis population.
18 citations
,
October 2014 in “Experimental Dermatology” Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
18 citations
,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” The authors concluded that increased expression of the HSD11B1 gene in adipose tissue correlates with obesity markers and predicts insulin resistance, but this association is independent of polycystic ovary syndrome when adiposity is controlled for.
18 citations
,
November 2010 in “Journal of morphology” This research examined the ultrastructure of deer hair fibers and found significant variations in diameter, cuticle thickness, and intermediate filament arrangements among different fiber types.
17 citations
,
May 2021 in “Journal of Assisted Reproduction and Genetics” This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.
17 citations
,
August 2019 in “Archives of Cardiovascular Diseases” In this study, the authors observed that testosterone therapy shortened the QTc interval and normalized T-wave morphology in men with acquired LQTS or TdP linked to hypogonadism, suggesting testosterone may be helpful in treatment.
17 citations
,
August 2018 in “BMC Genomics” The researchers found that HOXC13 regulates different keratin proteins in a mixed manner, with certain SNPs impeding this regulation, while also demonstrating negative-feedback by HOXC13 and positive regulation by LEF1 and melatonin on the HOXC13 promoter.
17 citations
,
June 2016 in “Croatian Medical Journal” In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.
16 citations
,
July 2020 in “International Journal of Molecular Sciences” This study found that ruxolitinib modulated inflammatory changes and stimulated growth factor signals by blocking the JAK-STAT pathway in an in vitro model of alopecia areata.
16 citations
,
May 2019 in “International Journal of Women's Dermatology” This study reviewed and categorized dermatological drugs for pregnancy and lactation according to new FDA labeling guidelines, which replaced simplistic letter categories with detailed information, aiming to improve prescribing decisions by addressing both maternal and paternal reproductive potential.
16 citations
,
February 2018 in “European Journal of Endocrinology” This review discusses the challenges in measuring testosterone for assessing androgen excess in women and emphasizes the importance of quality control in laboratory methods, but it reports no new clinical results.
16 citations
,
December 2017 in “Journal of Pediatric and Adolescent Gynecology” In this study, the researchers found that the choice of diagnostic criteria significantly affects the rate of PCOS diagnosis in adolescents.
16 citations
,
April 2017 in “ACM Transactions on Graphics” Light scatters differently from elliptical hair fibers than from circular ones, and a new model better predicts this behavior, especially for shiny highlights.
16 citations
,
November 2016 in “Journal of Cosmetic and Laser Therapy” This review highlights that laser and light treatments could serve as safe and effective alternatives to current therapies for alopecia areata, with the excimer laser showing positive results, though further randomized controlled trials are necessary to establish optimal treatment protocols.
16 citations
,
October 2009 in “Dermatology” This study found that a cream containing spironolactone did not affect hair growth in hirsute women.