August 2022 in “Nature Biotechnology” This report highlights Amvuttra's approval for hATTR amyloidosis as a more convenient RNAi therapy, and Olumiant's attention as the first systemic drug for hair loss among recent developments.
April 2020 in “Journal of The American Academy of Dermatology” In this study, to address long wait times for alopecia specialists, researchers implemented shared medical appointments for women with female pattern hair loss, modeled on formats previously used for conditions like acne and vitiligo.
127 citations
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December 2005 in “Experimental Dermatology” This study provides evidence that psychoemotional stress inhibits hair growth in mice by affecting the brain-hair follicle axis, with specific neuropeptides and treatments modulating this effect.
54 citations
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August 2005 in “Alcohol” This study found that acute finasteride treatment decreased ethanol intake in male C57BL/6J mice, whereas chronic treatment showed diminished effects, implying compensatory changes in neurosteroid modulation.
36 citations
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January 2019 in “Nature communications” This study found that Ldh activity in hair follicle stem cell-mediated squamous cell carcinoma is not necessary for tumorigenesis, as its modulation did not affect the cancer's development or characteristics.
35 citations
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October 2012 in “Dermatologic Clinics” This article reviews the impact of different forms of alopecia on patients with systemic autoimmune diseases and reports no new clinical findings; it emphasizes the need for attentive management of alopecia-related symptoms.
5 citations
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September 2020 in “Molecules” In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.
January 2026 in “Frontiers in Medicine” This study found that acupuncture may reduce anxiety and depression in women with polycystic ovary syndrome, potentially through hormonal and neuroendocrine modulation, but further high-quality research is needed to confirm these findings.
January 2024 in “Research Square (Research Square)” This study reports that adjusting the valence states of Mo in Pluronic F127-coated MoO3-x nanozymes enhances their selective H2O2-related catalytic activity, showing promise in acute kidney injury treatment and enabling real-time monitoring of therapy effectiveness through ROS-responsive photoacoustic imaging.
45 citations
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June 2018 in “Frontiers in immunology” This study found that MDSC exosomes promoted partial hair regrowth and modulated immune responses in mice with alopecia areata, suggesting potential as a treatment for autoimmune diseases.
10 citations
,
January 2024 in “Polymer Chemistry” This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.
3 citations
,
January 2024 in “Materials advances” This article reviews the properties of cellulose nanocrystals for sustainable development but presents no new experimental results.
September 2025 in “Frontiers in Microbiology” This review discusses targeting gut microbiota modulation as a promising strategy for osteoarthritis prevention and management but reports no new clinical findings.
July 2025 in “Nano Research” This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.
9 citations
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June 2021 in “Journal of Inflammation Research” This study found that Euph E and Euri A showed strong anti-inflammatory activity and modulated cytokine and immune functions in macrophages, related to specific signaling pathways.
2 citations
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November 2020 in “Ciencia Tecnología y Salud” This review discusses the potential application of platelet-rich plasma (PRP) therapy as a regenerative treatment approach, particularly as an alternative and complementary therapy for severe respiratory conditions, though clinical protocols are needed to verify its efficacy.
July 2026 in “Archives of Dermatological Research” This study explores the potential of adaptogenic herbal extracts like ashwagandha, rhodiola, and schisandra in treating stress-induced dermatoses, noting their effects on modulating the HPA axis, reducing inflammation, and improving skin barrier function.
May 2025 in “International Society of Hair Restoration Surgery” This study suggests that exosomes derived from mesenchymal stem cells may promote hair growth and improve skin health by enhancing dermal papilla cell proliferation and modulating inflammation and oxidative stress.
28 citations
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January 2017 in “EBioMedicine” This study discusses potential anti-inflammatory roles of endocannabinoid system modulation and phytocannabinoids in skin health, but reports no new clinical results; the authors emphasize the need for further clinical exploration.
May 2025 in “Antioxidants” This review highlights how natural products with antioxidant properties can modulate the Wnt signaling pathway, potentially influencing various pathological conditions such as cancer, stroke, and regenerative medicine. It also addresses controversies in the compounds' mechanisms across different models and suggests research directions for future studies.
54 citations
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October 2024 in “Nature Communications” In this study, researchers developed a method to control the valence states of Mo in nanozymes, optimizing their activity for ROS-related therapies, particularly acute kidney injury treatment, and enabling real-time monitoring with photoacoustic imaging.
6 citations
,
November 2023 in “Chinese Medicine” This study found that Xinyang Tablet may improve cardiac function in LPS-induced sepsis-induced myocardial dysfunction by modulating macrophage polarization and autophagy through affecting LncSICRNT1 and TRAF6 expression.
April 2026 in “Preprints.org” The study found that enhancing quercetin bioavailability with EubioQuercetin may amplify its anti-aging effects in mice by modulating the gut microbiota and improving intestinal barrier function.
January 2024 in “Biological Research” This study found that mesenchymal stem cell-derived exosomes reduced hearing and hair cell loss caused by neomycin in experimental models by modulating autophagy, which promoted cell survival and lowered oxidative stress and apoptosis, indicating potential for deafness treatment.
January 2024 in “Clinical dermatology open access journal” This paper reviews existing research on the cosmetic benefits of hemp-derived cannabinoids for skin and hair, highlighting their unique mechanisms of action, while discussing formulation, legal, and regulatory challenges associated with using these compounds in cosmetic products.
December 2023 in “European Journal of Medicinal Chemistry” This review highlights potential therapeutic mechanisms of natural products for androgenetic alopecia, suggesting they may modulate signaling pathways and have anti-inflammatory and antioxidant effects.
October 2023 in “Biomaterials” This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.
49 citations
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October 2024 in “Frontiers in Immunology” In this review, the authors highlighted the potential of natural polysaccharides from plants, animals, and microbes to modulate immune responses, reduce inflammation, and strengthen the intestinal barrier, suggesting their promising role as immunomodulatory agents in pharmaceutical applications.
11 citations
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June 2018 in “Annales de dermatologie et de vénéréologie” This narrative review discusses adverse reactions associated with hair care products, specifically irritation dermatitis and allergic contact eczema, and suggests the need for attention to common allergens like PPD, GMTG, and ammonium persulphate.
139 citations
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May 2020 in “Stem Cell Research & Therapy” In this study, human bone marrow mesenchymal stem cell-derived exosomes significantly accelerated cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.