This study found that the Nap-F3K-CA hydrogel, when used on burn wounds, demonstrated effective antibacterial and anti-inflammatory properties, promoting accelerated skin repair, decreased wound infections, and improved healing processes, highlighting its potential as a clinical burn wound dressing.
June 2024 in “Regenerative Therapy” This review highlights the potential of exosomes as a novel therapeutic approach for skin diseases and aging, due to their stability, transportability, and ability to carry various bioactive compounds to target cells.
This study synthesized new heterocyclic steroid derivatives and reported their promising antiproliferative activity against breast and prostate cancer cell lines, highlighting selectivity and impact on signaling pathways even in cells resistant to certain treatments.
July 2023 in “Stem Cells Translational Medicine” This review discusses the roles of mesenchymal stem cells in wound healing, particularly their interactions with immune cells, and highlights the potential and current limitations of MSC-based therapies for tissue regeneration.
October 2020 in “Authorea (Authorea)” This review discusses the influence of androgens on opioid-mediated effects and calls for further research into their role in sex differences and potential therapeutic options for chronic pain and substance use disorders.
1 citations
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March 2023 in “Science Translational Medicine” The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.
May 2026 in “ACS Catalysis” In this study, researchers using QM/MM simulations identified key molecular motions and residue interactions in the enzyme SRD5A2 that significantly influence its catalytic efficiency, demonstrating that specific residues play critical roles in stabilizing transition states and reducing activation barriers.
November 2025 in “Advanced Science” In this study, researchers developed a polyphenol–amino acid nanozyme capable of controlled hydrogen peroxide delivery, which effectively activated hair follicles via oxidative stress in a mouse model, suggesting a potential non-pharmacological treatment for alopecia.
19 citations
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September 2013 in “Psychoneuroendocrinology” Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
11 citations
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August 2021 in “Stem Cell Research & Therapy” This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.
5 citations
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September 2024 in “International Journal of Molecular Sciences” This study used a 3D bioprinted human lung cancer model in a mouse phantom to demonstrate a selective cytotoxic effect of X-rays on tumor cells, revealing differences from 2D cell models.
5 citations
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November 2022 in “Diversity” This review highlights the potential of indigenous southern African foods rich in phytochemicals and soluble dietary fibers to combat cardiovascular disease in economically disadvantaged urban populations in South Africa by improving dietary diversity and affordability.
4 citations
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February 2025 in “Pharmaceuticals” In this study, voglibose, commonly used for diabetes management, was found to reduce melanin synthesis and inhibit melanogenic signaling pathways in B16F10 melanoma cells, suggesting it could be repurposed for treating hyperpigmentation disorders with confirmed topical safety in human tests.
1 citations
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August 2025 in “Molecules” This review synthesizes research on hederagenin's anticancer and anti-inflammatory potential, emphasizing chemical modifications to enhance its bioactivity, but reports no new experimental findings.
1 citations
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July 2025 in “Journal of Cosmetic Dermatology” This case report suggests that exosome therapy may offer a promising alternative treatment for lichen planopilaris, showing potential benefits in hair regrowth, reduced inflammation, and improved scalp condition, but further studies are needed to confirm long-term efficacy and safety.
May 2026 in “International Journal of Molecular Sciences” In this review, researchers explore the roles of lactoferrin in skin and hair health, highlighting its potential anti-inflammatory and regenerative benefits despite the lack of well-controlled clinical trials for hair-specific outcomes.
February 2026 in “Food Research International” Lactiplantibacillus plantarum ZJUIDS51 can help regrow hair and improve scalp health in androgenic alopecia.
1 citations
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June 2024 in “Frontiers in Physiology” This bibliometric study analyzed publications on endoplasmic reticulum stress and atherosclerosis, revealing key research areas and emerging trends in the field without reporting new experimental results.
This review categorizes contractile hydrogels by their contraction mechanisms and explores their role in advanced wound management, emphasizing mechanical and biochemical signaling in healing, but also notes challenges like force transmission and clinical applicability.
August 2026 in “Molecular Biomedicine” This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.
February 2025 in “Biomolecules” This research found that melatonin has a bidirectional effect on hair follicle stem cell survival, improving it at low doses and inhibiting it at high doses.
848 citations
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October 2020 in “International Journal of Molecular Sciences” This review discusses the potential of platelet-rich plasma applications in regenerative medicine and explores recent progress and challenges in translating non-clinical PRP findings into human treatments, but reports no new clinical results.
142 citations
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March 2019 in “Molecules/Molecules online/Molecules annual” This review discusses the role of the endocannabinoid system in skin health and disease, highlighting its potential for future research and applications, but reports no new experimental results.
114 citations
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January 2021 in “medRxiv (Cold Spring Harbor Laboratory)” This meta-analysis estimated that around 80% of patients who had COVID-19 experienced at least one long-term symptom, with fatigue being the most common reported effect.
40 citations
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September 2024 in “Heliyon” This review discusses the role of bioceramics, highlighting their bactericidal activity, lack of side effects, and ability to release metallic ions for hard and soft tissue repair. The authors suggest that integrating bioceramics with other biomaterials could offer a cost-effective, efficient alternative for wound healing.
34 citations
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November 2020 in “Biomedical Physics & Engineering Express” This study observed that using DNA nanostructures to deliver chemotherapy drugs could potentially reduce costs compared to traditional methods, with financial barriers being less significant than technical, regulatory, and ethical challenges.
30 citations
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February 2023 in “Journal of Investigative Dermatology” OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.
30 citations
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July 2021 in “Annals of Botany” This study observed that maize plants enhance phosphorus acquisition by promoting both root hair growth and lateral root development in response to localized nutrient patches, highlighting a complementary root trait trade-off.
28 citations
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April 2024 in “Immunity” In this study, researchers found that hair follicle stem cells activate an immune-modulatory program during wound healing, promoting Treg cell expansion and aiding skin repair, while deleting certain immune components impaired healing and increased inflammation in a mouse model.
28 citations
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April 2023 in “Stem cell research & therapy” This study reviews the roles and mechanisms of MSC-derived exosomes in wound healing, noting their potential as promising cell-free therapies for cutaneous regeneration.