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Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Doctors need to be better prepared to assess and treat obesity in patients.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Minoxidil use in children may cause heart issues.

Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.