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New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Wound healing is complex and requires more research to enhance treatment methods.

The PRP-like cosmetic with biomimetic peptides is potentially effective and safe for treating alopecia areata.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Juniperus plants contain compounds with potential for developing various medical treatments.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.

Mollusc egg extract helps skin and hair cells grow and heal.

Metformin may help treat neuroendocrine tumors.

ZO-1 helps hair follicle stem cells renew better by changing their structure.

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.

Peptides from oysters may safely and effectively heal skin wounds with less scarring.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Tyrosine Kinase Inhibitors are effective against cancer but can cause skin, digestive, and blood side effects, including hair loss.

Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.

A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.