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Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

Alternating treatment with two drugs could help cells in a rapid aging disease.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

Minoxidil can reduce functions related to androgen receptors.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Costunolide helps human hair cells grow and can stimulate hair growth in mice.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.

Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.

Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Caffeine may help reduce stress-induced hair loss.

A new mouse mutation causes skin and hair defects due to a gene change.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.