October 2020 in “Revista médica sinergía/Revista médica sinergia” Alopecia areata is a complex condition causing hair loss, linked to genetics and immune system issues, and may be related to other autoimmune diseases; treatments vary in effectiveness.
December 2011 in “Drug Research” The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
July 2019 in “The European research journal” RDW can be a useful marker for inflammation in alopecia areata patients.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Certain nutrients can improve skin health and treat skin problems safely.
2 citations,
February 2023 in “Actas Dermo-Sifiliográficas” A 31-year-old man with severe atopic dermatitis (AD) and multilocular alopecia areata (AA) showed significant improvement after switching from dupilumab to baricitinib treatment. Despite previous ineffective treatments, baricitinib, a JAK inhibitor, led to marked improvement in AD symptoms and hair regrowth in AA areas within 4 weeks, with sustained progress at 12 weeks. The case highlights baricitinib's efficacy in treating both AD and AA, conditions linked by shared immunological pathways, and underscores the potential of JAK inhibitors in managing diverse immunomediated diseases. Baricitinib was well tolerated, with only mild seborrhea reported as a side effect.
4 citations,
January 2019 in “Einstein (São Paulo)” Dupilumab improved severe atopic dermatitis in a patient who didn't respond to other treatments.
6 citations,
January 2019 in “Journal of feline medicine and surgery open reports” A cat with severe skin issues improved with dexamethasone and cetirizine.
2 citations,
September 2022 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” For sensitive scalp, treatment is personalized and may include specific medications and hydration, while avoiding stress and irritating products.
38 citations,
September 2017 in “Journal of zoo and wildlife medicine” Oclacitinib maleate successfully treated alopecia in Andean bears.
13 citations,
April 2019 in “Actas Dermo-Sifiliográficas” Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.
1 citations,
December 2022 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Sensitive scalp causes discomfort and hair loss, treated with personalized care.
59 citations,
October 2016 in “Clinics in dermatology” Precise skin sampling is crucial to understand the role of P. acnes in acne.
54 citations,
July 1994 in “Journal of Dermatological Science” The study investigated the hair growth-stimulating effects of Cyclosporin A (CsA) and FK506, both potent immunosuppressants. CsA was known to cause excessive hair growth (hypertrichosis) in various conditions, including alopecia areata and male-pattern alopecia, through both topical and oral administration. FK506, while not causing hypertrichosis orally, significantly stimulated hair growth when applied topically on animals, indicating a mechanism separate from its immunosuppressive effects. FK506 was found to directly stimulate hair follicles in vitro, suggesting its potential as a hair growth stimulant, though its effectiveness in humans was not yet clear.
36 citations,
January 2015 in “Clinical and Translational Allergy” Humans and pets share similar allergy mechanisms, and studying pet allergies can help treat both human and animal allergies.
13 citations,
October 2004 in “Anais Brasileiros De Dermatologia” The document concludes that compulsive hair disorders, like trichotillomania, are complex and require careful diagnosis and treatment from both psychiatric and dermatological perspectives.
4 citations,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
1 citations,
January 2020 in “Journal of Feline Medicine and Surgery Open Reports” Ciclosporin A effectively treated a cat's severe skin condition.
365 citations,
November 2018 in “Journal of Allergy and Clinical Immunology” People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
115 citations,
November 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.
115 citations,
October 2009 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.
91 citations,
January 2010 in “Journal of Allergy and Clinical Immunology” NK cells play a role in skin diseases like eczema and psoriasis.
63 citations,
March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
53 citations,
January 2018 in “JAAD case reports” Dupilumab for eczema may cause hair loss.
43 citations,
June 2018 in “Clinics in dermatology” People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.
37 citations,
October 2017 in “Clinical and Experimental Dermatology” Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.
33 citations,
January 2019 in “Acta Dermato Venereologica” Dupilumab may help regrow hair in people with atopic dermatitis.
31 citations,
July 2017 in “Journal of the American Academy of Dermatology” Apremilast improved symptoms in patients with severe skin conditions.
27 citations,
March 2018 in “Allergy and asthma proceedings” People with alopecia areata often have higher rates of allergies and autoimmune diseases.
25 citations,
May 2019 in “Biologics” Dupilumab can cause rare side effects like a rash on the face and neck.
25 citations,
December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Targeted cytokine treatments may help with alopecia areata, but more research is needed.