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This study reviewed the literature on atopic dermatitis and found a strong connection with several other skin conditions, such as psoriasis and alopecia areata, while highlighting potential treatments like JAK inhibitors and dupilumab that show promise for these comorbidities.

This study reported that in a case series of three adolescents with alopecia areata and atopic dermatitis, treatment with 15 mg/day of upadacitinib led to rapid improvement in skin symptoms and significant hair regrowth over 12 months, with no severe adverse events observed.

This review discusses the pathological factors and comorbidities associated with androgenetic alopecia and reports no new clinical results, emphasizing the need for improved understanding and treatment in clinical practice.

In this study, researchers did not find any genome-wide significant genetic signals linked to comorbid chronic inflammatory disorders in patients with alopecia areata, but exploratory analysis suggested potential associations worth further study.

This study suggests pediatric patients with alopecia areata may benefit from screening for atopic, autoimmune, and psychiatric comorbidities to enable timely identification and treatment.

This study found that 90% of pediatric patients with alopecia areata had comorbidities, including allergic rhinitis and atopic dermatitis, with localized AA being associated with better treatment outcomes and fewer relapses compared to non-localized forms.

This study reviews the epidemiology of alopecia areata in the UK, focusing on its links to mental health comorbidities, autoimmune/atopic associations, and common infection incidences.

This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.

This literature review found that pediatric patients with vitiligo may have increased risks of conditions such as atopic dermatitis, alopecia areata, autoimmune thyroid disease, and psychiatric disorders, impacting their quality of life. Screening should consider these risks for effective management.

Hospitalizations for atopic dermatitis are more due to other health issues now, not the condition itself.

In this study, CCCA patients were found to have higher odds of metabolic, autoimmune, atopic, and psychiatric comorbidities compared to matched controls.

This study found that the prevalence of alopecia areata in Japan increased from 2012 to 2019, with allergic diseases as common comorbidities and a need for more effective treatments, particularly for severe and pediatric cases.

This study found that, in Germany between 2016 and 2020, alopecia areata had an annual prevalence of 210 cases per 100,000 and an incidence of 72 cases per 100,000, with higher rates in specific regions and associated with comorbidities like atopic dermatitis and psoriasis.

In this study, researchers examined the prevalence of comorbid conditions among 402 alopecia areata patients, finding that hypothyroidism was notably more frequent in women, while hyperlipidemia was more common in men, with overall thyroid function testing suggested for these patients.

In this systematic review, researchers found that individuals with lichen sclerosus have a higher prevalence of comorbidities like vitiligo, alopecia areata, and cardiovascular diseases compared to non-affected controls, and suggest screening all LS patients for cardiovascular risk factors and other diseases.

This study found that from 1990 to 2021, the global age-standardized prevalence, incidence, and years lived with disability of alopecia areata decreased, with females being more affected, and highlighted the importance of addressing psychological disorders in children with alopecia areata under age 14.

This study suggests that certain climate factors, particularly UV index and precipitation, may influence seasonal flare patterns in children with alopecia areata, especially those with atopic conditions.

This review highlights recent literature on comorbidities in dermatologic diseases, emphasizing the need for further research into connections between atopic dermatitis and pancreatic cancer, and pemphigus diseases and COPD, but it reports no new clinical results.

In this observational study, researchers examined U.S. and Canadian patients with alopecia areata and found that while comorbid anxiety/depression correlated with increased patient-reported disease severity, other comorbidities like atopic dermatitis and vitiligo showed no statistically significant differences in clinician-reported AA severity or hair involvement.

This study found that patients with alopecia areata had similar total health care costs as those with atopic dermatitis, despite having fewer comorbidities and prescription medications overall.

This study found that alopecia areata patients in Central Europe with comorbid chronic inflammatory disorders, especially atopic dermatitis, bronchial asthma, or Hashimoto's thyroiditis, had an increased likelihood of experiencing early-onset, severe, or prolonged disease compared to those without such comorbidities.

This study suggests that female patients with alopecia areata, especially those with nail abnormalities and atopic diseases, have a higher prevalence of autoimmune disease comorbidities.

This review highlights potential links between inflammatory skin diseases like psoriasis and atopic dermatitis and hypercoagulable states, but notes that more research is needed to understand these connections and their clinical implications.

This review discusses the significant burden of disease and psychosocial implications associated with alopecia, highlighting its comorbidities and the impact on quality of life despite being viewed traditionally as an aesthetic concern, but reports no clinical results.

This narrative review highlights the shared immunopathogenesis of alopecia areata and atopic dermatitis and discusses approved and investigational therapies that target common pathways, suggesting a future for personalized treatment strategies.

This study found that Finnish individuals with alopecia areata, especially those with significant hair loss, reported reduced well-being and significant comorbidities, highlighting unmet needs for treatment and professional support.

This study in Singapore found that alopecia areata generally does not significantly impact the quality of life for pediatric patients and their families, with better outcomes observed in those with comorbidities like allergic rhinitis.

In a study conducted on 257 Latin American patients with alopecia areata, researchers found that the most frequent lesion location was the scalp, affecting 86.1% of participants, and reported multiple associated comorbidities, notably cardiovascular and endocrine diseases, with certain conditions being more common in women.

This review discusses the correlation between vitiligo and various autoimmune, systemic, and dermatological diseases, highlighting the need to increase awareness of these comorbidities.

This study found that individuals with AA have a higher incidence of atopic and autoimmune conditions, suggesting both Th1 and Th2 immune responses may play a role in its development.