research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
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research Metabolic Study of Androsta-1,4,6-Triene-3,17-Dione in Horses Using Liquid Chromatography/High Resolution Mass Spectrometry
The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.
research A New Label-Free Screen for Steroid 5α-Reductase Inhibitors Using LC-MS
Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
research The Evolution of Primary Multimodality Treatment in Resectable Breast Cancer
Multimodal primary treatment improves survival in premenopausal breast cancer patients and is also beneficial for postmenopausal women.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Viable Terminal Scalp Hair Follicles Are Necessary and Sufficient for Clinical Efficacy of Finasteride in Male Pattern Hair Loss
Finasteride works for hair loss by maintaining existing hair follicles, not reversing miniaturization.
research African Baobab (Adansonia Digitata) Fruit as a Promising Source of Procyanidins
African baobab fruit is a good source of antioxidants and micronutrients, but too much can cause laxative effects.
research Placebo-Controlled Dose-Effect Studies with Topical Minoxidil 2% or 5% in Male-Patterned Hair Loss Treated with Oral Finasteride Employing an Analytical and Exhaustive Study Protocol
Minoxidil 5% works better than 2% for hair growth in male-patterned hair loss.
research Chromatographic Methods for Determination of Finasteride and Tamsulosin Hydrochloride in Presence of Finasteride Degradation Product
Two methods can measure finasteride and tamsulosin hydrochloride; HPLC is more advantageous, while TLC offers better separation.
research A Novel Approach to Manage Skin Toxicity Caused by Therapeutic Agents Targeting Epidermal Growth Factor Receptor
New treatment with green tea polyphenols and nicotinamide improves skin problems from cancer therapy.
research Microbial Oxidation of Finasteride with Macrophomina Phaseolina (KUCC 730)
research A New Aliphatic Ester of Hydroxysalicylic Acid from Fermented Carica Papaya L. Preparation with Potential Hair Growth Stimulating Activity
A new compound from fermented papaya may help stimulate hair growth.
research Quantifying Polymer Deposition on Hair Fibers by Microfluorometry
Microfluorometry effectively measures how much polymer coats and penetrates hair, useful for evaluating hair products.
research Biotransformation of Finasteride (MK-0906) by Selenastrum Capricornutum (Green Algae)
Green algae can break down finasteride, reducing environmental harm.
research Biomimetics Through Bioconjugation of 16-Methylheptadecanoic Acid to Damaged Hair for Hair Barrier Recovery
16-MHA can restore the barrier and moisture of damaged hair, making it similar to undamaged hair.
research Isolation and Structural Characterization of Degradation Products of Finasteride by Preparative HPLC, HRMS, and 2D NMR
Finasteride forms three new products under acidic stress.
research Serotoninergic And Melatoninergic Systems Are Fully Expressed In Human Skin
Human skin can make serotonin and melatonin.
research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
research A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
research Phytochemical Analyses of Ziziphus Jujuba Mill. Var. Spinosa Seed by Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry and Gas Chromatography-Mass Spectrometry
The study found that Ziziphus jujuba seeds contain beneficial compounds for treating insomnia and anxiety and that the methods used are effective for assessing their quality.
research Geranylated Coumarins From Thai Medicinal Plant Mammea Siamensis With Testosterone 5α-Reductase Inhibitory Activity
Compounds from the plant Mammea siamensis may help treat hair loss.
research Bioactive Compounds from the Roots of Asiasarum Heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
research Towards Best Practice in Hair Metabolomic Studies: Systematic Investigation on the Impact of Hair Length and Color
Hair color and length affect metabolite profiles in hair, so they should be considered in hair analysis.
research Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS
Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
research Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS
The method can measure vitamin B3 levels in human hair accurately.
research Omics for Precious Rare Biosamples: Characterization of Ancient Human Hair by a Proteomic Approach
The study developed a method to analyze ancient hair proteins using very small samples.
research Study on the Mechanism of Cadmium Chloride Pollution Accelerating Skin Tissue Metabolism Disorder, Aging and Inhibiting Hair Regeneration
Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
research Extractives of Cercidiphyllum Japonicum Twigs: Isolation and Structural Elucidation of a New Galloylflavonol Glycoside, Anomeric Tannins and Flavonoids
Scientists found a new natural compound and other known compounds in Cercidiphyllum japonicum twigs, which might be useful for medicine.
research High-Resolution Mass Spectrometric Investigation of the Phase I and II Metabolites of Finasteride in Pig Plasma, Urine, and Bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study
New method measures finasteride in plasma, finds two formulations bioequivalent.