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Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Different types of skin cells play specific roles in development, healing, and cancer.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Stem cell self-renewal is complex and needs more research for full understanding.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Different types of stem cells and their environments are key to skin repair and maintenance.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.