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The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Androgens can help prevent memory problems caused by apoE4.

Stem cell niches support, regulate, and coordinate stem cell functions.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

The circadian clock influences the behavior and regeneration of stem cells in the body.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.