9 citations
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November 2007 in “Blood” This study found that a mutation in the Tmprss6 gene disrupts hepcidin regulation, leading to iron deficiency and alopecia in mice, highlighting TMPRSS6's vital role in iron absorption.
8 citations
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November 2012 in “Blood” This study observed that the incidence of hair loss as a spontaneously reported side effect of novel oral anticoagulant therapy is approximately 4.4 per 100 patient years.
4 citations
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December 2016 in “Blood” This study describes a case of cyclic thrombocytopenia where a novel MPL gene mutation may contribute to the disease, with gene expression changes in platelet and neutrophil genes preceding platelet count fluctuations.
3 citations
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December 2016 in “Blood” This study found PRP treatment significantly increased hair count and anagen hairs in male patients with androgenetic alopecia, but there was no correlation between therapeutic response and platelet or growth factor levels.
2 citations
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November 2004 in “Blood” In this study, researchers reported that the Pinkie mutation in mice, affecting RXRa activity, leads to skewed Th1 development and suggests RXRa's role in Th2 differentiation, impacting immune responses.
1 citations
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November 2024 in “Blood” This study found that inhibiting the PI3Kδ enzyme in murine models of cutaneous chronic graft-versus-host disease (cGVHD) reduced skin scores and fibrosis, prevented pathogenic lymphoid structures, and improved survival, suggesting it as a promising therapeutic approach to address the disease's hypoxic pathophysiology.
Low vitamin C caused bleeding and corkscrew hair, resolved with vitamin C treatment.
The study found that the combined administration of regulatory T cells and rapamycin improved outcomes in an experimental model of chronic graft-versus-host disease.
This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.
This study found that mutations in the TMPRSS6 gene affect the ability of matriptase-2 to inhibit hepcidin, which may impact the molecular pathogenesis of iron-refractory iron-deficiency anemia.
This study found that administering gingerol improved survival and reduced organ damage in mouse models of chronic graft-versus-host disease by modulating T cell differentiation and inflammatory cytokines, suggesting a novel therapeutic approach for steroid-refractory cases.
September 2025 in “Blood Advances” This study found that targeting androgen receptors with prostate cancer drugs ARN509 and finasteride induced remission and increased survival in a leukemia mouse model, suggesting a potential new treatment approach for acute myeloid leukemia.
This study found that a short-term treatment with all-trans retinoic acid may effectively stabilize platelet counts in idiopathic thrombocytopenic purpura patients experiencing fluctuations during thrombopoietin receptor agonist therapy.
This study suggests that raising the lower normal serum ferritin level to 50 ng/mL may improve organ functions even when hemoglobin levels are normal.
This study found that prophylactically administering amotosalen-treated allogeneic donor T cells at transplantation significantly improved immune reconstitution and protection against murine cytomegalovirus infection without inducing graft-versus-host disease.
This study concluded that the combination of all-trans-retinoic acid and tocopherol-α is not recommended for treating del(5q) myelodysplastic syndromes due to low efficacy and high incidence of adverse effects.
This study found that CMV infection in a mouse model of allogeneic transplantation was associated with increased allo-reactive T cell expansion and exacerbated graft-versus-host disease, highlighting the need for effective GvHD prophylaxis and treatment.
14 citations
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November 2013 in “Journal of the American Society for Horticultural Science” This study observed that glycine inhibited root growth and stimulated root hair development in habanero pepper seedlings, with ethylene signaling suggested to mediate these effects.
December 2023 in “ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE” In this study, PCOS patients had lower Spexin levels, which were inversely associated with adverse metabolic and hormonal profiles, suggesting a role for Spexin in PCOS pathways.
May 2017 in “American Society of Health-System Pharmacists eBooks” This abstract provides definitions and descriptions of various medical and scientific terms but reports no new research findings.
July 2005 in “HortScience” This study found that adding sheep wool-waste or human hair-waste to soil increased yields and secondary metabolites in various crops and supported up to five harvests without additional fertilizers, though it decreased mycorrhizae colonization.
This case report describes a 21-year-old woman with systemic lupus erythematosus who developed lupus nephritis in the context of thrombotic microangiopathy, including a rare presentation of cryoglobulin-like thrombi.
578 citations
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April 1993 in “Cell” This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.
418 citations
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September 2012 in “Nature” This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.
197 citations
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January 2019 in “Neuropsychopharmacology” This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.
161 citations
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June 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the switch-off of melanogenesis during the hair cycle in C57 BL-6 mice is a gradual and stochastic process starting in mid anagen VI, with specific biochemical markers indicating the transition to catagen.
155 citations
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May 2016 in “Nature communications” This study found that mouse skin CD4(+) memory T cells are in equilibrium with the circulation under steady state but increase in specific clusters in response to infection or inflammation.
136 citations
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September 2019 in “Journal of Clinical Investigation” This study found that mature dermal adipocytes have high plasticity, undergoing dedifferentiation and redifferentiation, which plays a significant role in hair cycling and wound healing.
124 citations
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November 2019 in “International Journal of Molecular Sciences” This review discusses different processing methods for isolating human AD-SVFs/AD-MSCs using various kits and reports no new clinical results, highlighting the need for standardized preparation techniques.