March 2025 in “International Journal of Trichology” This literature review found that Janus kinase inhibitors may help achieve remission in patients with refractory primary neutrophilic cicatricial alopecias, though data is limited to small case series and reports.
January 2025 in “Journal of Drugs in Dermatology” This study highlights consensus statements from an expert panel, emphasizing the overlooked role of scalp barrier health in hair growth and dandruff, and notes that most prior research has focused on inflammatory diseases rather than dandruff.
November 2024 in “JAMA Dermatology” This consensus statement provides expert guidance on prescribing low-dose oral minoxidil for hair loss, noting a lack of representation of pediatric specialists and highlighting areas for future research.
November 2024 in “SKIN The Journal of Cutaneous Medicine” In this study, NH Asian alopecia areata patients reported the highest levels of severe disease, with NH White patients having the most eyebrow involvement and Hispanic patients showing the least severity.
November 2024 in “SKIN The Journal of Cutaneous Medicine” In this observational study, researchers examined U.S. and Canadian patients with alopecia areata and found that while comorbid anxiety/depression correlated with increased patient-reported disease severity, other comorbidities like atopic dermatitis and vitiligo showed no statistically significant differences in clinician-reported AA severity or hair involvement.
November 2024 in “SKIN The Journal of Cutaneous Medicine” This study found that generic quality of life questionnaires, like the SF-36 and DLQI, are not sensitive enough to detect differences in health-related quality of life between patients with varying severity of alopecia areata.
November 2024 in “Journal of Drugs in Dermatology” This review found that platelet-rich plasma may have a positive effect on scarring alopecia by slowing progression and reducing inflammation, though evidence remains limited to case reports.
October 2024 in “Skin Appendage Disorders” This study found no overall side preference for hair growth on the scalp, yet many healthy individuals tend to grow more hair on one side, suggesting that genetics and possibly behavioral or environmental factors may influence this pattern.
August 2024 in “JAAD Case Reports” This article reviews the current FDA-approved treatments for severe pediatric alopecia areata, including the use of Janus kinase inhibitors, but reports no new clinical findings.
August 2024 in “JAMA Dermatology” In this study, withdrawal of baricitinib therapy in patients with severe alopecia areata who had achieved hair regrowth led to a loss of benefit in almost all patients, suggesting that continued treatment is necessary to maintain hair regrowth.
January 2024 in “Pharmacoepidemiology” This study found that patients with rheumatoid arthritis taking tofacitinib had higher rates of serious adverse events compared to those with alopecia areata, highlighting the need for careful assessment when using it off-label for alopecia areata.
January 2024 in “American journal of clinical dermatology” This study reports that ritlecitinib, when used for up to 24 months in patients aged 12 and older with alopecia areata, has an acceptable safety profile, with a similar proportion of adverse events in both ritlecitinib and placebo groups in the placebo-controlled cohort.
January 2024 in “JEADV clinical practice” This article reviews how SALT scores are used in clinical trials for alopecia areata and provides patient images to help clinicians understand and apply these scores in practice; it reports no new clinical results.
November 2023 in “Dermatologic Surgery” Lasers might help regrow hair in people with hair loss due to genetics.
This study found that at Week 52, baricitinib resulted in significant hair regrowth for many patients with severe alopecia areata, with 41.6% on the higher dose achieving substantial improvement in scalp hair loss, though some may need longer treatment for optimal benefit.
September 2023 in “Journal of the American Academy of Dermatology” This review discusses the potential of platelet-rich plasma for treating scarring alopecias and reports no clinical results; the authors emphasize the need for further research.
September 2023 in “Journal of the American Academy of Dermatology” CTP-543 is generally safe for treating alopecia areata.
September 2023 in “Journal of the American Academy of Dermatology” CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.
July 2023 in “Journal of the American Academy of Dermatology” This study found significant differences in enrollment and completion rates among racial and ethnic groups in alopecia areata clinical trials, with Black patients showing lower enrollment and higher dropout rates compared to other groups.
March 2023 in “International journal of trichology” This review discusses genetic conditions linked to complete scalp alopecia in children, identifying six genetic causes, but reports no new clinical results.
February 2023 in “Journal of Drugs in Dermatology” In this literature review, researchers found evidence that topical melatonin may improve scalp hair growth, density, and thickness in patients with androgenetic alopecia, especially in men.
September 2021 in “Fertility and Sterility” This study found that older men in North America had longer infertility durations and were more likely to have partners who underwent IVF, with age impacting referral patterns and substance use behaviors.
August 2021 in “Journal of the American Academy of Dermatology” This article reviews the use of hair filler fibers for improving the appearance of thinning hair and calls for more studies on patient satisfaction and side effects, without providing new clinical results.
August 2021 in “Journal of the American Academy of Dermatology” This review discusses the use of rice bran extracts from Oryza sativa in cosmetic hair products and notes a lack of scientific evidence supporting their effectiveness in enhancing hair growth.
June 2021 in “International journal of cosmetics and dermatology” This review found limited support for oral vitamin C and E in treating pigmentary disorders like chloasma, inflammatory conditions, and pressure wounds, with evidence constrained by small, varied studies.
April 2021 in “Research Square (Research Square)” This study concluded that achieving 80% or more scalp hair, corresponding to a SALT score of ≤20, represents a clinically meaningful treatment success for patients with alopecia areata experiencing ≥50% hair loss.
More research is needed to confirm PRP's effectiveness for scarring alopecia.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study evaluated current treatments for pediatric alopecia areata and found that high potency topical steroids had the strongest supporting evidence, with promising results also observed for anthralin ointment and other treatments in lower-grade studies.
December 2018 in “International journal of women’s dermatology” This study found significant alterations in the scalp and gut microbiome of patients with alopecia areata compared to healthy controls, suggesting a potential link to systemic inflammation and autoimmune response.
This study shows that multiphoton microscopy can non-invasively distinguish scarring from non-scarring alopecia by identifying specific morphological features in hair follicle structures.