December 2025 in “International Journal of Pharmacology” This review highlights that iPSC-derived artificial platelets offer a promising alternative to platelet-rich plasma for regenerative medicine, with standardized manufacturing and reproducible pharmacological properties, addressing variability issues associated with donor-derived platelets and showing therapeutic potential in preclinical models of osteoarthritis.
2 citations
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March 2024 in “JAAD Case Reports” In this study, platelet-rich plasma treatments over three months were reported to improve hair growth in individuals with androgenetic alopecia, although objectively measuring its efficacy remains challenging.
April 2021 in “Journal of Investigative Dermatology” This study explored the use of an AI-driven device, HairMetrix, to quantitatively assess the effects of PRP treatments on scalp health in two Caucasian women with androgenetic alopecia, reporting increases in average hair width and follicle count after one treatment.
July 2025 in “Clinical Dermatology Review” This study found that platelet-rich plasma therapy led to significantly increased hair growth and density compared to placebo in patients with androgenic alopecia over six months.
This review discusses the integration of robotics and AI in robotic follicular extraction for hair transplantation, highlighting improved precision and efficiency but reports no new clinical results.
August 2024 in “Dermatological Reviews” This review discusses how emerging technologies in dermatology are enhancing the ability to diagnose and treat hair and nail disorders more accurately and effectively, highlighting advancements in both diagnostic techniques and therapeutic methods such as AI-driven technologies that personalize patient care and improve outcomes.
January 2006 in “Basic & Clinical Medicine” In this study, injection of hair keratin artificial material into rats did not significantly affect leucocytes or blood plates compared to normal saline, suggesting its histocompatibility.
September 2020 in “British Journal of Dermatology” This article provides issue information for the September 2020 edition of the British Journal of Dermatology and contains no new research findings.
July 2025 in “Russian Journal of Transplantology and Artificial Organs” This research highlights advancements in reconstructive surgery for managing scars, emphasizing the importance of combined surgical and nonsurgical interventions like platelet-rich plasma and stem cell therapy to prevent and treat thick scar tissue while enhancing functionality and aesthetic outcomes.
1 citations
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February 2021 in “Journal of Dermatological Treatment” The researchers reviewed artificial hair implantation's history and controversies, noting that studies show promise but suffer from poor methodology. They emphasized the need for higher-quality research to confirm the procedure's safety and efficacy.
25 citations
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January 2018 in “Acta Clinica Croatica” This study found that allogeneic platelet gel significantly improved healing in non-healing chronic lower leg ulcers compared to hydrogel treatment.
March 2026 in “Frontiers in Pharmacology” The study concluded that the Exprecell™ device for preparing anticoagulant-free f-PRF increases volume yield and simplifies the process while maintaining biological activity comparable to conventional methods, suggesting potential clinical utility.
January 2026 in “Frontiers in Cell and Developmental Biology” This review discusses the molecular mechanisms and clinical applications of autologous platelet-derived products for TMJ regeneration, but reports no new clinical results.
In this book, the authors provide an accessible overview of platelet concentrates and their dental applications, highlighting their role in tissue healing and regeneration, and reviewing recent studies on their efficacy in periodontal therapy, implant dentistry, and oral surgery.
October 2025 in “Frontiers in Immunology” This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.
October 2025 in “Dermatology Practical & Conceptual” This study found that ChatGPT 4.0 and Gemini 1.5 Flash provided more accurate and user-friendly responses to androgenetic alopecia questions than Deepseek R1, suggesting they could be effective tools for patient education with physician guidance.
1 citations
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January 2019 in “The International Journal of Lower Extremity Wounds” This study demonstrated in rodent models that artificial dermal template treatment can induce full-thickness skin regrowth including skin epidermis and adnexa without the need for autologous skin grafts.
February 2026 in “Dermatology and Therapy” This narrative review found that while AI-based tools in dermatology, particularly for hair disorder assessment, have potential to enhance clinical practice by improving objectivity and personalization, they currently serve mainly a complementary role and face challenges like methodological limitations and data bias.
February 2025 in “Theranostics” In this study, researchers used 3D bioprinting with skin stem cells and specific hydrogels to create artificial skin that successfully promoted complete wound healing and the regeneration of skin structures, including hair follicles and blood vessels, in mice.
This review suggests that injectable platelet-rich fibrin therapy shows promise for improving hair density in androgenetic alopecia and enhancing facial skin texture and elasticity, but larger studies are needed to confirm its effectiveness.
November 2020 in “Journal of The American Academy of Dermatology” Oral health affects overall well-being, with tooth loss impacting quality of life, nutrition, and health.
70 citations
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February 2021 in “International Journal of Molecular Sciences” This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.
29 citations
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September 2020 in “International Journal of Molecular Sciences” This review outlines the current state of freeze-dried platelet-rich plasma (FD-PRP) research, emphasizing its use in wound healing, lumbar fusion, knee conditions, and dentistry, but reports no new clinical findings.
16 citations
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January 2021 in “International Journal of Medical Sciences” This study found that gelatin microspheres loaded with platelet-rich plasma enhanced wound healing in rats by improving inflammatory and angiogenic responses compared to untreated wounds or PRP alone.
12 citations
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April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
12 citations
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January 2013 in “IOSR Journal of Agriculture and Veterinary Science” In this study, homogenous platelet rich plasma gel improved wound healing in goats, showing organized collagen and new hair growth within 15 days without inflammation.
9 citations
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May 2024 in “Cureus” This review discusses the role of platelet-rich plasma in assisted reproductive technology for enhancing endometrial receptivity and reports promising outcomes.
4 citations
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October 2024 in “BMC Oral Health” This review suggests that PRF may be a promising alternative treatment for oral mucosal lesions, but further research is needed to confirm its long-term effectiveness and standardize preparation protocols.
3 citations
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May 2023 in “Current Molecular Medicine” This review discusses the distinction between platelet-rich plasma and stem cell-based therapies in regenerative medicine, highlighting their different roles and stressing the importance of honest representation by commercial and health entities.
March 2026 in “Trends in Sciences” This review suggests that while platelet-rich plasma has the most robust clinical evidence, platelet-rich fibrin and concentrated growth factors are gaining favor due to their ease of use and absence of additives.