5 citations
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January 2012 in “Indian Journal of Dermatology Venereology and Leprology” Werner's syndrome causes early aging and increases cancer risk, requiring early diagnosis and symptom management.
December 2007 in “Röntgenpraxis” This review discusses various treatments for androgenic alopecia, highlighting FDA-approved options and other commonly used therapies, but reports no new clinical results.
June 2019 in “Brain Imaging and Behavior” In this study, androgenic alopecia was identified as an independent predictor of abnormal white matter hyperintensities in the brain, suggesting it may serve as a surrogate marker for cerebral small vessel disease linked to arteriolosclerosis.
23 citations
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March 2010 in “Actas Dermo-Sifiliográficas” In this study, early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid atherosclerosis compared to controls, suggesting cardiovascular screening might be beneficial for this group.
1 citations
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August 2009 in “ACTUALIDAD MEDICA” In this study, early-onset androgenetic alopecia patients showed a higher prevalence of metabolic syndrome and carotid atheromatosis compared to a control group, suggesting the need for cardiovascular risk screening in this population.
February 2009 in “Journal of The American Academy of Dermatology” People with early-onset hair loss have higher risk of heart issues, so early screening is important.
February 2009 in “Journal of The American Academy of Dermatology” AGA patients have higher rates of metabolic syndrome and carotid atheromatosis, suggesting early screening and prevention is important.
This study found that early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid arteriosclerosis compared to controls.
4 citations
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May 2020 in “Cureus” This case report describes an adult male from India with Werner's syndrome due to a novel homozygous mutation in the WRN gene, characterized by several premature aging symptoms.
January 1998 in “Lasers in Surgery and Medicine” This study found that both 5-ALA and Photofrin can effectively destroy human microvascular endothelial cells in vitro and cause tissue necrosis in vivo, with Photofrin showing greater efficacy at lower concentrations or power densities.
12 citations
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March 2017 in “Arteriosclerosis, thrombosis, and vascular biology” This study in male mice found that testosterone provides strong protection against skin necrosis after ischemia, working through its estrogenic and androgenic derivatives to enhance skin survival and revascularization, with 17β-estradiol being notably more effective than dihydrotestosterone.
May 2023 in “Arteriosclerosis, thrombosis, and vascular biology” In this study, finasteride significantly reduced plasma cholesterol and triglycerides and decreased atherosclerotic lesion burden in mice, suggesting its potential role in delaying cardiovascular disease.
2 citations
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September 2015 in “Clínica e Investigación en Arteriosclerosis” This review discusses the association between certain dermatological diseases and increased cardiovascular risk, highlighting the need for clinicians to address cardiovascular risk factors in these patients.
3 citations
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May 2018 in “Biochemical and Biophysical Research Communications” In this study, researchers found that inhibiting inducible nitric oxide synthase (iNOS) promoted hair growth in diabetic mice, suggesting iNOS-derived nitric oxide contributes to hair loss under diabetic inflammatory conditions.
72 citations
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October 1998 in “Baillière's clinical endocrinology and metabolism” This article discusses the potential effects of exogenous testosterone, highlighting that its impact on prostate cancer progression, cardiovascular health, and behavior remains uncertain and needs further investigation.
44 citations
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August 2017 in “Food Bioscience” This study found that betasitosterol-loaded nanostructured lipid carriers, when added to butter, improved its nutritional profile and antioxidant properties, maintaining stability over a three-month storage period.
24 citations
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November 2015 in “Annals of Nutrition and Metabolism” This study found that specific SHBG gene variants and haplotypes are associated with polycystic ovary syndrome, suggesting that SHBG may be a candidate gene for the condition.
22 citations
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March 1932 in “Journal of the American Medical Association” This report describes eleven cases of thallium poisoning in individuals who consumed tortillas made from barley mixed with thallium sulphate, leading to symptoms including tingling, abdominal pain, vomiting, and limb weakness.
21 citations
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January 2006 in “Pediatrics” This review discusses how certain genetic, infectious, and metabolic conditions might influence disease severity and highlights the potential for new therapies, but it presents no new research findings.
15 citations
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July 2012 in “Biological trace element research” This study found that an increased calcium/magnesium ratio in hair and lower chromium concentration were associated with higher insulin resistance in Korean adult males.
15 citations
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May 2010 in “Actas Dermo-Sifiliográficas” This study found that men with early-onset androgenetic alopecia had a higher prevalence of metabolic syndrome and carotid atheromatous plaques than control subjects, suggesting a need for cardiovascular screening in this group.
12 citations
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February 2016 in “Biochemical and Biophysical Research Communications” This study found that sulforaphane treatment enhanced hair regeneration in ob/ob mice by increasing DHT-degrading enzyme levels and lowering plasma testosterone and DHT.
1 citations
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January 2006 This study found a positive association between bilateral diagonal earlobe crease and bilateral preauricular crease with coronary artery disease, with both creases together predicting the disease with 90% accuracy.
1 citations
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February 1954 in “Journal of the American Geriatrics Society” Steroid hormones can help treat aging issues and improve health in elderly people.
March 2012 in “Pathy's Principles and Practice of Geriatric Medicine” Older adults often have skin problems due to aging, and treating these conditions requires attention to both physical and mental health.
June 2016 in “International journal of recent surgical and medical science” This study found that early-onset male androgenetic alopecia was associated with a higher prevalence of metabolic syndrome compared to age-matched controls.
11 citations
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January 1995 in “Biomedicine & pharmacotherapy” This review discusses the use of finasteride and alpha antagonists for symptomatic benign prostatic hypertrophy and suggests current studies are evaluating combination therapies as potential non-surgical alternatives.
25 citations
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June 2015 in “Scientific Reports” In this study, patients with alopecia areata were found to have a higher risk of stroke over a 3-year follow-up period compared to those without the condition.
This study introduced Cadd4, a peptide-based degrader developed using computer-aided drug design, which effectively reduced PCSK9 levels and increased LDL receptor expression, resulting in decreased plasma cholesterol and LDL-C levels in hypercholesterolemic mice, without liver toxicity.
January 2010 in “Ciencia UANL” This study found a significant relationship between androgenetic alopecia and insulin resistance-associated indicators like obesity in young men, suggesting a potential risk for developing cardiovascular and metabolic disorders.