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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Researchers created human hair follicles using a new method that could help treat hair loss.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Special fiber materials boost the healing properties of certain stem cells.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Zinc is effective for treating various skin conditions, including warts and acne.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.