68 citations
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May 2013 in “The American journal of medicine” This report documents two cases of severe systemic poisoning from heavy metals after short-term use of traditional Chinese medicines for treating damaged or infected tissue.
67 citations
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January 2007 in “Environmental health perspectives” This case report highlights that a woman experienced arsenic toxicosis from kelp supplements, manifesting as alopecia and memory loss, which resolved after stopping the supplements.
22 citations
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November 2002 in “Clinical journal of oncology nursing” This article discusses arsenic trioxide as a treatment for refractory or relapsed acute promyelocytic leukemia, noting its effectiveness and manageable side effects.
17 citations
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January 1993 in “Dermatology” This report describes two cases of chronic arsenicism, one involving criminal poisoning by a sibling and the other associated with prolonged use of Fowler's solution.
5 citations
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March 1992 in “PubMed” In this study, researchers found that arsenic transfer to induced hair in rats increased sharply at first and then more gradually, correlating significantly with arsenic levels in key organs.
1 citations
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July 2021 in “Small ruminant research” This study found that supplementing arsenic-fed Black Bengal kids with vitamin E, alone or combined with yeast culture, partially ameliorated growth and reduced arsenic load in faeces, urine, and hair.
February 2026 in “International Journal of Homoeopathic Sciences” In this case report, a 40-year-old male with keratosis pilaris showed progressive improvement in skin texture and reduction of symptoms after individualized homoeopathic treatment with Arsenicum album 30C, but further studies are needed to assess its general effectiveness.
April 2026 in “International Journal of Advanced Biochemistry Research” This study assessed mice's hematology and serum enzymes under sodium arsenite toxicity and observed that Aegle marmelos fruit extract reduced liver and kidney damage, mitigating the toxin's effects by maintaining normal enzyme levels when both were administered together.
September 2016 in “Case Reports in Internal Medicine” This case report presents a patient with diabetes mellitus thought to be secondary to chronic arsenic exposure, highlighting the potential need to evaluate heavy metal toxicity in similar cases.
This review discusses fractionated reirradiation as a potential treatment for recurrent brain tumors in children and highlights ongoing challenges with managing craniospinal dissemination; it provides no new clinical results.
1 citations
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February 2002 in “Oncology Times” This research reports that arsenic trioxide achieved a complete remission rate of 87% in patients with relapsed acute promyelocytic leukemia, though its use involves manageable toxicities.
May 2011 in “British Journal of Dermatology” The 1891 epidemic skin disease was likely caused by arsenic poisoning, possibly from beer or fish.
February 2025 in “Archives of Dermatological Research” In this study, researchers administered injectable platelet-rich fibrin (i-PRF) to 30 patients with androgenetic alopecia, finding an 80% response rate after 6 months, with improved hair density and reduced scalp symptoms, while reporting minimal adverse reactions.
January 2024 in “Bioanalysis” November 2023 in “IntechOpen eBooks” This source highlights that arsenic exposure through contaminated groundwater is a significant global health risk, leading to skin and hair conditions such as pigmentation changes, skin irritation, alopecia, and can eventually result in skin cancer.
30 citations
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October 2020 in “Frontiers in Plant Science” In this study, the combination of arsenic toxicity and hypoxia in Arabidopsis thaliana altered root development through stress-specific root growth phenotypes and changes in phosphate starvation response, energy metabolism, and redox signaling.
This research presentation explored the roles of mammalian multi-copper ferroxidases in iron homeostasis and highlighted new insights into their functions, including non-iron-related ones, while discussing arsenic's role in microbial warfare as a potential antibiotic.
8 citations
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March 2023 in “PubMed” This review discusses JAK inhibitors as promising new treatments for various chronic dermatologic conditions, including some recent drug approvals, and reports no new clinical results.
1 citations
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October 2022 in “The American Journal of Gastroenterology” This case study describes a 29-year-old woman whose severe liver injury was primarily attributed to chronic arsenic exposure, highlighting the importance of recognizing metal toxicity in patient care.
3 citations
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August 2021 in “Journal of Cosmetic Dermatology” This study found that non-ablative Er:YAG laser treatment, alone or combined with other therapies, effectively improved hair quality and reduced AGA grade in patients, with high satisfaction reported and no adverse reactions.
January 2016 in “Renal Failure” Kidney stones and hair loss are significantly related in people under 60 years old.
66 citations
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January 2001 in “Vitamins and hormones” This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.
65 citations
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August 2016 in “Metabolic brain disease” This study found that children with autism spectrum disorder generally have lower levels of both essential and toxic trace elements in their hair compared to controls.
37 citations
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February 2010 in “Psychoneuroendocrinology” This study found that nuclear androgen receptors are not necessary for androgen self-administration, suggesting that plasma membrane receptors might be involved.
26 citations
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January 2018 in “Skin appendage disorders” This review summarizes existing studies on toxic agents that can cause alopecia, with thallium and colchicine having the most established links, while others like botulinum toxin A need further investigation.
25 citations
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November 2013 in “PLoS ONE” This study demonstrates that locally synthesized estrogen and androgen neurosteroids play opposite roles in long-term synaptic changes in male rats' medial vestibular nucleus, with testosterone-dihydrotestosterone mediating long-term depression and 17β-estradiol mediating long-term potentiation.
16 citations
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January 2015 in “Forensic science international” This study found that two pre-Hispanic mummies from the Andean coast had well-preserved hair with significant amounts of heavy metals like iron, lead, bromide, and occasionally arsenic, revealing their historical context.
16 citations
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April 1985 in “Archives of dermatology” This review discusses various treatments for pityriasis rubra pilaris, including vitamin A, methotrexate, and systemic steroids, reporting historical anecdotal evidence without new clinical results.
13 citations
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April 1994 in “Journal of Investigative Dermatology” Androgen receptors found in monkey scalps, similar to humans, affect hair growth.