September 2017 in “Asian Journal of Beauty and Cosmetology” The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.
November 2016 in “Oncology Letters” Milia may come from the outer part of the hair follicle.
March 2014 in “Anais Brasileiros de Dermatologia” Hair follicles are a key source of stem cells for skin repair and could help treat baldness.
March 2024 in “Journal of clinical medicine” Trichoscopy shows hair diameter variability, vellus hairs, and the peripilar sign are key indicators for diagnosing Androgenetic Alopecia.
Male androgenetic alopecia (MAA) is a common, hereditary hair loss condition in men, linked to heart disease, and can be treated with minoxidil, finasteride, or hair transplantation.
June 2020 in “Journal of Drugs in Dermatology” Frontal fibrosing alopecia can be misdiagnosed as androgenetic alopecia in African American women.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
45 citations,
April 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
24 citations,
January 2018 in “Indian Journal of Dermatology, Venereology and Leprology” Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.
949 citations,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
73 citations,
January 2002 in “Journal of Investigative Dermatology” Epidermal stem cells don't use gap junctions to communicate.
24 citations,
November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
2 citations,
May 2021 in “European medical journal” Botulinum toxins are safe for various medical and cosmetic uses, but more research is needed for long-term safety and effectiveness in hair growth treatments.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
1010 citations,
August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
245 citations,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
222 citations,
August 2009 in “Experimental Dermatology” Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
161 citations,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
139 citations,
September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
128 citations,
August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
114 citations,
January 2016 in “Current topics in developmental biology/Current Topics in Developmental Biology” Frizzled receptors are essential for various body development processes and maintaining certain body functions.
64 citations,
January 2009 in “The International journal of developmental biology” Hair follicle stem cells are controlled by their surrounding environment.
55 citations,
March 2010 in “Aging” Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
53 citations,
July 2016 in “Cosmetics” Future hair cosmetics will be safer and more effective.
47 citations,
November 2000 in “Archives of dermatology” Pulsed infrared laser can effectively reduce symptoms of pseudofolliculitis barbae.
45 citations,
April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
44 citations,
January 2013 in “BMC Dermatology” TGFβ signaling prevents sebaceous gland cells from producing fats.
41 citations,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
35 citations,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.