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Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

Chitosan nanoparticles loaded with Minoxidil were effective for hair growth but released the drug more slowly than the amphiphilic derivative.

Hormonal imbalances are important in the development of male pattern baldness.

About one-third of Saudi women with female pattern hair loss also have thinning hair at the back of their head.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Testosterone may slow down wound healing and increase inflammation.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.