The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
January 2005 in “Вестник Оренбургского государственного университета” This study found that minoxidil combined with all-trans retinoic acid additively promoted hair growth in vitro by enhancing cell survival and reducing apoptosis compared to minoxidil alone.
7 citations
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September 2023 in “Cancer Treatment Reviews” This review highlights the possible impact of side effects from endocrine therapy on quality of life, emphasizing that these can lead to poor adherence and early treatment discontinuation in patients with hormone receptor positive early breast cancer, potentially worsening survival outcomes.
December 2023 in “International journal of molecular sciences” This in vitro study found sex chromosome differences affect steroidogenic enzyme activity and androgen receptor expression in human skeletal muscle cells, showing varied responses to testosterone exposure between 46XY and 46XX cells.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
December 2005 in “Current Prostate Reports” This review discusses the historical and current use of androgen manipulation for treating benign prostatic hyperplasia and reports no new clinical results.
December 2018 in “Journal of Medicinal and Aromatic Plant Sciences” This review discusses various plants being investigated for their potential in hair growth promotion and highlights the need for more research, reporting no new clinical results.
39 citations
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June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” This review examines around 68 plant sources from six major plant families, assessing their scientific rationale and use by the cosmeceutical industry for applications like anti-ageing and sun protection.
1 citations
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January 2013 in “International Journal of Medicinal and Aromatic Plants” In a rabbit study, flaxseed oil applied topically significantly increased hair width, while flaxseed ingestion also had a positive effect, but neither method improved hair length or weight.
May 2024 in “Current perspectives on medicinal and aromatic plants” This mini review explores the potential of herbal testosterone 5α-reductase inhibitors for treating androgenetic alopecia, suggesting they might offer fewer side effects and better tolerability than traditional treatments like finasteride and minoxidil.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
December 2021 in “International journal of minor fruits, medicinal and aromatic plants” This review identifies common medicinal plant species in Sri Lankan home gardens and discusses their traditional Ayurvedic uses, but it reports no new clinical results.
15 citations
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September 2018 in “Indian Research Journal of Pharmacy and Science” This article reviews the historical and therapeutic aspects of aromatherapy, discussing its effects on psychological and physical well-being but providing no new clinical findings.
October 2010 in “Reproductive Biomedicine Online” A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.
3 citations
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September 2018 in “MOJ Toxicology” This review discusses the medicinal properties of Alpinia zerumbet Roxb. and highlights its potential for further research, but provides no new clinical results.
3 citations
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January 1985 in “British Journal of Dermatology” In this study, a low concentration zinc sulphate solution was investigated for managing recurrent herpes simplex infections, but no new clinical results were reported.
2 citations
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January 1997 in “Principles of Medical Biology” This article reviews the role of enzymatic processes in drug and toxin metabolism, emphasizing their impact on solubility and elimination, without presenting new clinical findings.
This study reviews the potential of rosemary extract for promoting hair growth and reducing hair fall, noting that its efficacy is comparable to minoxidil and that it is generally safe for topical use, though further clinical trials are needed to standardize formulations and dosages.
27 citations
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October 2011 in “British Journal of Dermatology” This study builds on previous findings by associating female pattern hair loss with gene polymorphisms related to oestrogen activity, suggesting oestrogen's role in the condition.
This article discusses tretinoin, noting its approved use for acne and photoaging and its broader application in treating various dermatological conditions, but reports no new clinical findings.
6 citations
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April 2013 in “Alternative and Complementary Therapies” Raspberry ketone lacks sufficient human research to support health benefit claims and requires more rigorous studies to confirm its safety and effectiveness.
December 2012 in “한국피부미용향장학회지” This study suggests that aroma oils categorized by scalp type have similar chemical compositions, potentially enhancing their effectiveness in aromatherapy for scalp issues.
45 citations
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August 2005 in “Bioorganic & medicinal chemistry” This study found that novel androgen antagonists incorporating a carborane moiety showed anti-androgenic activity comparable to flutamide in a laboratory setting.
31 citations
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October 2020 in “Journal of nanomaterials” This study suggests that silver nanoparticles synthesized using Grewia optiva leaf extract exhibit stronger antibacterial and antioxidant properties than the leaf extract alone.
28 citations
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September 2000 in “Journal of Medicinal Chemistry” This study identified novel compounds as selective inhibitors of the type 1 isoenzyme of 5α-reductase, displaying promising potential for treating DHT-dependent disorders such as acne and androgenic alopecia.
19 citations
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April 2024 in “Journal of Umm Al-Qura University for Applied Sciences” This review explores the diverse roles of rosemary, covering its nutritional and medicinal uses, cosmetic and pharmaceutical applications, and evaluates various extraction methods, with a focus on sustainable practices and commercial prospects.
19 citations
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September 1995 in “Food and nutrition bulletin” This article reviews the toxic effects of mimosine in Leucaena leucocephala and discusses various methods to mitigate its toxicity but presents no new findings.
12 citations
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February 2010 in “Tetrahedron Letters” This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.
12 citations
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June 2003 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the range and management of adverse cutaneous reactions to psychotropic medications and emphasizes the need for awareness among clinicians, concluding with a call for careful monitoring and patient education.
7 citations
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January 2015 in “Dermatology” This study found that specific CYP19A1 gene SNPs were significantly associated with female pattern hair loss risk in a Chinese Han population.