January 2006 in “Casopís lékar̆ů c̆eských” This article reviews the characteristics of female androgenetic alopecia, highlighting its hormonal and genetic factors, and reports no new experimental findings; the authors note various life stages when hair loss may occur.
295 citations
,
March 2016 in “Life Sciences” This review discusses the links between particulate matter exposure and skin diseases, highlighting oxidative stress and inflammation as key mechanisms; it reports no new clinical results.
98 citations
,
February 2021 in “Dermatologic Therapy” This review explores how air pollutants may contribute to various skin diseases and highlights potential mechanisms, but it presents no new clinical findings.
70 citations
,
June 2023 in “International Journal of Molecular Sciences” In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.
23 citations
,
August 2019 in “Proceedings of the National Academy of Sciences of the United States of America” Pollution exposure speeds up hair damage.
7 citations
,
January 2015 in “Hair therapy & transplantation” This review discusses the impact of air pollution on hair loss and sensitive scalp syndrome, evaluating possible causes and management strategies, but reports no new clinical results.
4 citations
,
April 1986 in “Cancer Letters” This study found no significant difference in glutathione-S-epoxide transferase activity in hair follicles between smokers and non-smokers, suggesting this enzyme's levels may not indicate polycyclic aromatic hydrocarbon-related cancer risk.
1 citations
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December 2023 in “Environmental pollution” This study quantified around 60 organic pollutants in hair samples from mothers and infants in Spain, finding significant correlations between pollutant levels and factors like residence, dietary habits, and maternal age, with common exposure sources identified for several pollutant classes.
December 2023 in “PubMed” This study highlights that homemade topical herbal preparations, although popular for their perceived safety, may lead to allergic reactions, notably with Mediterranean herbs, and advises cautious use, particularly for allergy-prone individuals.
November 2023 in “Scholars journal of applied medical sciences” This study conducted in Rabat surveyed 100 individuals with afro-textured hair to identify plant-based treatments, finding twelve plant species purportedly effective in managing hair issues, with Ricinus communis, Cocos nucifera, and Aloe barbadensis being the most frequently cited.
This study found that compounds isolated from Indian medicinal plants showed good to moderate hair growth activity in vivo compared to minoxidil.
155 citations
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October 2002 in “The FASEB Journal” This study found that altered testosterone metabolism and changes in cytochrome P450 mono-oxygenase expression are significantly associated with cardiac hypertrophy in human hearts and spontaneously hypertensive rats.
77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
67 citations
,
October 2005 in “Annals of Oncology” This review found that fulvestrant is well tolerated in postmenopausal women with hormone receptor-positive advanced breast cancer, showing lower incidence of joint disorders than non-steroidal aromatase inhibitors.
31 citations
,
September 2006 in “International journal of gynaecology and obstetrics” This article reviews diagnostic criteria and treatment options for polycystic ovary syndrome, focusing on hormonal and metabolic management strategies, and presents no new clinical data.
25 citations
,
November 2013 in “PLoS ONE” This study demonstrates that locally synthesized estrogen and androgen neurosteroids play opposite roles in long-term synaptic changes in male rats' medial vestibular nucleus, with testosterone-dihydrotestosterone mediating long-term depression and 17β-estradiol mediating long-term potentiation.
24 citations
,
October 2012 in “The International Journal of Biochemistry & Cell Biology” In this study, testosterone protected female embryonic heart cells from metabolic stress by being converted into metabolites that activate estrogen receptors and up-regulate certain mitochondrial channel proteins.
7 citations
,
April 2023 in “Biomedicines” This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.
4 citations
,
March 2023 in “IP International Journal of Comprehensive and Advanced Pharmacology” This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.
1 citations
,
September 2013 in “PubMed” This case report suggests that methotrexate therapy for psoriasis may lead to hair regrowth in androgenetic alopecia, potentially due to its effects on testosterone metabolism.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study describes a rare instance of virilization during pregnancy in a woman with PCOS, with symptoms resolving post-delivery as testosterone levels normalized.
July 2019 in “Acta Scientiae Veterinariae” This case report describes a Canadian Husky dog with sertolioma that exhibited dermatological symptoms and aggressive behavior, both of which improved significantly after surgery.
22 citations
,
October 1996 in “Dermatologic clinics” This review summarizes recent advances in understanding intermediate filament structure and their implications for pathological mutations and human diseases, but it reports no new experimental results.
9 citations
,
January 1981 This study found that the alkaline degradation process of hair keratin using nucleophilic reagents led to different proportions of reaction products compared to wool, particularly more lanthionine and lysinoalanine residues.
18 citations
,
January 1994 in “Skin Pharmacology and Physiology” This review discusses the enzyme levels involved in dihydrotestosterone formation in androgenetic alopecia patients and reports no new results; the authors suggest these differences may lead to better treatments for men and women.
6 citations
,
June 2006 in “International Journal of Gynecological Pathology” This study reports that in a case of benign Brenner tumor, elevated androgens may originate from luteinized stromal cells, as these cells do not convert androgen to estrogen due to suppressed aromatase biosynthesis.
June 2025 in “Journal of the Faculty of Medicine Baghdad” This study found that Syzygium aromaticum oil may improve the anagen/telogen ratio in testosterone-induced alopecia in mice, indicating potential as an alternative treatment to minoxidil for androgenic alopecia.
66 citations
,
January 1987 in “Journal of Investigative Dermatology” This study found that enzyme activity critical to cancer induction by polycyclic aromatic hydrocarbons in human hair follicles increased after using a crude coal tar-containing shampoo for four days and was substantially inhibited by imidazole compounds.
57 citations
,
May 2021 in “Molecules” This review explores the chemical composition and biological activities of essential oils from selected aromatic roots, highlighting their potential for various industries, though more research is needed to standardize their bioactive components.
9 citations
,
January 1983 in “Journal of Chromatography B Biomedical Sciences and Applications” This study found that enzyme activity related to cancer induction by polycyclic aromatic hydrocarbons can be increased by using a shampoo containing crude coal tar and significantly inhibited by imidazole compounds in human hair follicles.