26 citations
,
July 2021 in “International journal of adolescent medicine and health” This review covers various treatments for managing PCOS symptoms and infertility, noting that aromatase inhibitors may be as or more effective than clomiphene citrate for ovulation induction but reports no new clinical results.
24 citations
,
May 2015 in “Molecular and clinical oncology” In this study, both honey and bee pollen may alleviate menopausal symptoms in breast cancer patients on antihormonal treatment, with no significant difference between the two.
24 citations
,
January 2011 in “Sexual Development” This study observed that chemically-induced intersex frogs displayed altered brain mRNA profiles, with finasteride increasing certain hormone-related gene expressions and fadrozole reducing aromatase activity without affecting gene transcript levels.
16 citations
,
June 2022 in “Transgender Health” This review suggests that oocyte retrieval may be viable for transgender men on testosterone therapy, with potentially manageable effects on fertility preservation without requiring extensive hormone suspension.
15 citations
,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
15 citations
,
October 2003 in “Annals of Oncology” Hair loss can occur as a side effect of certain breast cancer treatments, but minoxidil can help regrow hair.
14 citations
,
January 2018 Lifestyle changes and medical treatments can help manage infertility in women with PCOS.
13 citations
,
August 2016 in “Reproduction” In this study, nandrolone decanoate treatment in rats caused persistent diestrus and altered steroid receptor expression and sex hormones, especially at higher doses, with partial reversibility at lower doses over time.
11 citations
,
August 2020 in “Diabetes” This study found that testosterone enhances insulin secretion in human pancreatic islets by being converted into DHT and E2, processes that are necessary for this effect.
11 citations
,
July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” This review discusses the role of oestrogens in stimulating linear bone growth and pubertal changes in both boys and girls, highlighting their influence on the growth hormone-insulin-like growth factor axis; it reports no new clinical results.
11 citations
,
January 1991 in “Urology” This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.
10 citations
,
March 2019 in “Journal of neuroendocrinology” This study found that developmental changes in testosterone synthesis and gene regulation may explain age differences in corticosterone release in response to stress between adolescent and adult rats.
10 citations
,
October 2006 in “Expert Opinion on Emerging Drugs” This review discusses trends in testosterone therapy use for male hypogonadism and reports no new clinical results, noting a shift towards more convenient and physiological treatments.
10 citations
,
December 2005 in “Aktuelle Dermatologie” This study reported that after 7.5 months of treatment, topical Alfatradiol significantly increased anagen hair rates in women and men with androgenetic alopecia, with minimal side effects.
9 citations
,
April 2018 in “JAMA Dermatology” This abstract provided no research findings as it contains only website navigation and service information.
8 citations
,
May 2017 in “Current traditional medicine” This review explores the phytochemistry and phytopharmacology of Urtica dioica but reports no new experimental findings, focusing on its traditional uses and range of bioactive constituents.
7 citations
,
May 2016 in “SpringerPlus” This review suggests that treating endocrine therapy-induced hair loss in breast cancer patients with topical 5-alpha reductase inhibitors and supplements like Vitamin C and omega-3 fatty acids may be effective, but further studies are needed.
7 citations
,
March 2011 in “Expert Opinion on Drug Safety” This review discusses the efficacy and safety of exemestane as a treatment for estrogen-receptor-positive breast cancer and reports no new clinical results.
6 citations
,
September 2012 in “Clinical Interventions in Aging” This study found that honokiol inhibits enzymes related to testosterone degradation in vitro, suggesting its potential as a lead compound for developing antiaging bioactive ingredients for men.
4 citations
,
August 2021 in “Clinical and Experimental Reproductive Medicine” This review highlights key clinical recommendations from the 2018 international guidelines on PCOS management and questions if these guidelines will be widely adopted in practice.
4 citations
,
August 2019 in “General and Comparative Endocrinology” This study found that in male yaks, 5α-red1 may play a crucial role in synthesizing DHT to promote hair follicle growth, while E2 synthesized by epithelial cells may inhibit this growth through ERα.
4 citations
,
May 2019 in “Biology open” This study found that while testosterone administration reduced myocardial damage in gonadectomized rats after ischemia/reperfusion injury, Finasteride led to greater improvements, whereas 4-hydroxyandrostenedione worsened outcomes.
4 citations
,
March 2019 in “JAT. Journal of applied toxicology/Journal of applied toxicology” In this study, PFOS exposure altered steroid hormone levels and enzyme activities related to steroidogenesis in juvenile Silurana tropicalis, with effects differing between male and female frogs.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” This summary reviews the conflicting reports regarding 17β‐estradiol's effects on hair follicle growth, highlighting potential estrogen receptor-mediated impacts and calling for further research.
3 citations
,
January 2018 in “Frontiers in bioscience” This retrospective analysis reported significant increases in testosterone levels in men with testosterone deficiency using the Daily Subcutaneous Testosterone method combined with hCG and anastrozole, indicating its potential as a treatment option.
3 citations
,
July 2014 in “Indian Journal of Surgery” Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.
2 citations
,
March 2011 in “Infertility” This review highlights that while lifestyle changes may help with many ovulatory disorders, oocyte donation is considered a viable option for patients who cannot undergo ovulation induction; it reports no new results.
1 citations
,
July 2022 in “Han'gug sigpum yeong'yang gwahag hoeji/Journal of the Korean society of food science and nutrition” In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.
1 citations
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March 2022 in “Daehanhanuihakoeji” In this study, Artemisia sieversiana extract was found to safely promote hair follicle dermal papilla cell growth and inhibit hair loss through anti-androgen, anti-inflammatory, and antioxidant effects at a cellular level.
1 citations
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January 2014 in “Side effects of drugs annual” Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.