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research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Oral Treatment of Keratinizing Disorders of Skin and Mucous Membranes With Etretinate
Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.
research Direct Access to Novel Chromeno-Pyrimidine-N-Oxides via Tandem Base Catalyzed Double Nucleophilic Addition/Dehydration Reaction
New method makes important drug ingredients more easily without needing extra purification steps.
research Relative Binding Affinity of Novel Steroids to Androgen Receptors in Hamster Prostate
New steroids were effective in blocking male hormone receptors in hamster prostates.
research Harnessing Herbal Ingredients in Hair Cosmetics: A Natural Approach to Hair Care
Herbal ingredients can effectively promote hair growth and improve hair health.
research Pomiferin: A Potent Stimulant of Extracellular Matrix Proteins
Pomiferin may improve skin and scalp health by boosting important protein expression.
research Air Pollution and Skin Diseases: Adverse Effects of Airborne Particulate Matter on Various Skin Conditions
Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.
research Human Pollution Exposure Correlates With Accelerated Ultrastructural Degradation of Hair Fibers
Pollution exposure speeds up hair damage.
research Understanding Hair Loss Due to Air Pollution and the Approach to Management
Air pollution can cause hair loss, and using antioxidants, special shampoos, and coconut oil can improve scalp health and hair density.
research Glutathione-S-Epoxide Transferase in Human Hair Follicles
GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.
research Chemical Examination of Three Indian Medicinal Plants and Their Hair Growth Evaluation Studies
Three Indian medicinal plant compounds help hair growth.
research Spigo Nardo: From the Este Herbarium a Possible Solution for Its Taxonomical Attribution
Researchers concluded that "spigo nardo" is the Himalayan plant Nardostachys jatamansi, used historically in medicine and cosmetics, now critically endangered.
research Lavenders: Their Phytochemical Properties and Uses for Medical and Cosmetic Purposes
Lavender is widely used for its calming effects and in beauty products, but its medical effectiveness is not fully proven and not FDA-approved.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Hair Regrowth in a Male Patient with Extensive Androgenetic Alopecia on Estrogen Therapy
Estrogen therapy helped regrow hair in a bald man.
research Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
research Standardization Of Sphagneticola Calendulacea (L.) Pruski Stem
The study established quality standards for Sphagneticola calendulacea stem and suggested it may have therapeutic benefits.
research Development and Evaluation of Virgin Coconut Oil-Based Herbal Hair Tonic
The VCO-based herbal hair tonic is effective, safe for hair loss treatment, and can be mass-produced.
research Investigation of Wrightia Tinctoria Extract Activity on Alopecia Using In-Silico and In-Vivo Studies
Wrightia tinctoria extract may promote hair growth better than minoxidil.
research Hair Keratinization in Health and Disease
Understanding intermediate filaments helps explain hair health and related diseases.
research Effects of Linum Usitatissimum L. Ingestion and Oil Topical Application on Hair Growth in Rabbit
Flaxseed ingestion and oil application help rabbit hair grow.
research A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia
Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.
research Low Concentration Zinc Sulphate Solution in the Management of Recurrent Herpes Simplex Infection
Zinc sulphate solution was not effective in reducing the number, duration, or severity of recurrent herpes simplex infections.
research Design and Synthesis of Novel Androgen Receptor Antagonists with Sterically Bulky Icosahedral Carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
![Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1](/images/research/ff6e6cbe-cb9c-4d11-87ef-671d28ffd4fa/small/15506.jpg)
research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1
Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
research Synthetic Studies Toward the Development of Novel Minoxidil Analogs and Conjugates with Polyamines
New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.
research Psychoactive Drugs and Skin
Some psychoactive drugs can cause skin reactions, with carbamazepine having a higher risk, and stopping the drug and seeing a dermatologist is important.