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This study found no evidence that the tested hair dye ingredients undergo hepatic metabolism to reactive oxidized metabolites in human liver microsomes and hepatocytes.

This study from Los Angeles supports the idea that using permanent hair dye may increase bladder cancer risk in US women, especially those with a slow NAT2 acetylation phenotype.

This study found that the alkaline degradation process of hair keratin using nucleophilic reagents led to different proportions of reaction products compared to wool, particularly more lanthionine and lysinoalanine residues.

This chapter reviews various types of aromatic compounds and provides references, but reports no new experimental results.

This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.

This study found that about 80% of known fullerene-binding proteins rank in the top 10% of scorers for C60 docking sites, confirming the accuracy of the predictive model used.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This study reports a new one-pot method for synthesizing chromeno-pyrimidine-N-oxides with high yield from 4-chloro-3-formylcoumarin and aromatic carboximide oximes, confirmed by X-ray analysis.

This review discusses the impact of air pollution on hair loss and sensitive scalp syndrome, evaluating possible causes and management strategies, but reports no new clinical results.

This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.

In this study, distinct metabolic profiles were identified in women with PCOS, suggesting potential biomarkers for diagnosis based on changes in lipid and androgen metabolism.

This study explored how modifying the 8-substituent of 8-bromobenzoquinolinone affects its selectivity in inhibiting both 5 alpha-reductase isozymes in the scalp.

This study synthesized a new organic sunscreen with broad photoprotective properties and demonstrated it to be non-toxic. The resultant cream, containing nanostructured lipid carriers, showed suitable application qualities and achieved a satisfactory SPF value of 16.

In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.

This study explored using tyrosine as a cross-linking agent for curling Asian hair and found that it could shape hair effectively before washing without damaging the fibers, though the method was less effective after washing compared to commercial products.

This review discusses Ayurvedic detoxification methods for poisonous plants, known as Visha Dravyas, and reports no new clinical results.

This study screened synthesized pyridinecarboxamides for antitumor properties and found that many, particularly 5c and 7a, showed moderate in vitro activity against various human tumor cell lines.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

This study reports that synthetic carbohydrate receptors effectively inhibit Zika virus infection in cell cultures by blocking early stages of viral entry.

This study found that microplastics on the Lebanese Mediterranean coast transport various organic and inorganic pollutants, posing threats to marine organisms and potentially human health.

This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.

In this review, Ziziphus lotus was reported to have multiple traditional uses and demonstrated various pharmacological properties in lab and animal studies, with over 181 identified bioactive compounds; however, clinical trials are needed to confirm its efficacy as a medicinal agent.

This study found that a nanotransferosome formulation of finasteride (FI-GO-NTF) in an Aloe vera gel significantly improved scalp permeation and antibacterial activity compared to standard formulations, suggesting safe and effective potential for alopecia areata treatment.

Certain ingredients in personal care products, like formaldehyde, oxidative hair dyes, and sulfates, pose health risks and need careful review.

This article reviews the role of enzymatic processes in drug and toxin metabolism, emphasizing their impact on solubility and elimination, without presenting new clinical findings.

This study found that mouse skin can produce and metabolize serotonin and N-acetylserotonin, with activity influenced by location, physiological skin status, cell type, and mouse strain.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

In this study, hair damaged by permanent dye showed signs of recovery over time, with near complete restoration to its original state after eight weeks.

In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.

This study found that adding 7% Ecklonia cava extract to oxidative hair dyes significantly reduced their cytotoxicity and oxidative stress without affecting color performance.