98 citations
,
July 1968 in “Archives of Dermatology” This study found that applying scalp sebum from young men to rabbit ear canals caused follicular hyperkeratosis, suggesting sebum stimulates the formation of comedones, a key feature in acne vulgaris.
88 citations
,
April 2011 in “Archives of Dermatology” This study found a high prevalence of central hair loss among African American women and associated it with diabetes mellitus type 2, bacterial scalp infections, and hairstyles causing traction.
84 citations
,
April 2002 in “Archives of Dermatology” This study found that a keratin mutation may cause diffuse partial woolly hair associated with loose anagen hair syndrome in some families, but other genetic factors could play a role in different cases.
82 citations
,
March 1994 in “Archives of Dermatology” This study found that a 2% topical minoxidil solution significantly increased hair regrowth compared to placebo in women with androgenetic alopecia over 32 weeks.
81 citations
,
August 1979 in “Archives of Dermatology” This case report describes a trichofolliculoma with perineural invasion, highlighting a rare and clinically significant finding in a typically benign hair follicle tumor.
78 citations
,
April 1984 in “Archives of Dermatology” This study found that 1% minoxidil topical solution led to terminal hair regrowth in some patients with alopecia areata, though it was only cosmetically acceptable in less than half of those cases.
75 citations
,
June 2005 in “Archives of Dermatology” In this case report, a patient experienced a recurrence of alopecia areata while undergoing etanercept treatment, suggesting the drug may not effectively prevent this condition's return.
74 citations
,
March 1963 in “Archives of Dermatology” This article reviews historical reports of skin changes, such as pseudoacanthosis nigricans, associated with cholesterol-lowering drugs like triparanol and nicotinic acid, but presents no new clinical findings.
73 citations
,
July 1977 in “Archives of Dermatology” In this case report, applying linoleic acid topically reversed essential fatty acid deficiency and related skin symptoms in a patient receiving long-term fat-free intravenous nutrition.
72 citations
,
November 2000 in “Archives of Dermatology” This study found that excision with primary closure is an effective surgical treatment for extensive acne keloidalis nuchae, with good cosmetic results and minimal recurrence observed among patients.
72 citations
,
October 1992 in “Archives of Dermatology” This study describes five patients whose cystic fibrosis was initially indicated by a rash associated with protein-energy malnutrition, highlighting the importance of early symptom recognition for timely diagnosis and treatment.
72 citations
,
October 1988 in “Archives of Disease in Childhood” This study found that while biotin treatment improves clinical and biochemical symptoms in patients with biotinidase deficiency, some experience lasting neurological damage, and it is uncertain if early treatment can prevent this.
69 citations
,
February 1987 in “Archives of Dermatology” This case report describes the topical application of cyclosporine in a man with alopecia universalis, which showed hair regrowth after 10 months of daily use, except where limited by a congenital nevus.
64 citations
,
December 1982 in “Archives of Dermatology” This article reviews various office treatments for common cosmetic issues but does not report any new clinical findings, focusing instead on discussing techniques like dermabrasion and chemical peels.
57 citations
,
December 1960 in “Archives of Dermatology” This introduction reviews historical use of steroids for alopecia treatment, mentioning early cases of hair regrowth with cortisone acetate but provides no new clinical data.
55 citations
,
February 1985 in “Archives of Dermatology” This study found that 32% of patients with hereditary male pattern baldness experienced cosmetically acceptable hair growth after applying topical minoxidil twice daily, with no serious side effects reported.
55 citations
,
February 1985 in “Archives of Dermatology” In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.
54 citations
,
November 1998 in “Archives of dermatology” This article discusses the potential role of nutritional ingredients, such as thiols and tannins, in triggering pemphigus, and reports no new empirical findings.
54 citations
,
February 1986 in “Archives of Dermatology” This study found that 5% topical minoxidil solution led to greater hair regrowth in severe alopecia areata patients compared to 1% minoxidil, although most regrowth was not cosmetically acceptable.
52 citations
,
February 1985 in “Archives of Dermatology” Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
50 citations
,
July 1981 in “Archives of Dermatology” This study found that applying dinitrochlorobenzene (DNCB), a contact allergen, led to hair regrowth in patients with alopecia areata, while croton oil did not have the same effect.
50 citations
,
July 1980 in “Archives of Dermatology” This report suggests that clinically inapparent sweat gland tumors might influence hair loss in a specific patient case.
47 citations
,
November 1966 in “Archives of Dermatology” This study found that trichorrhexis nodosa, a common cause of unexplained hair loss, is primarily caused by trauma rather than a metabolic defect.
44 citations
,
July 2004 in “Archives of Dermatology” In this study, treatment with 1 mg of finasteride was associated with stable sexual function, suggesting that sexual side effects may be less common than indicated in clinical trials.
44 citations
,
May 1980 in “Archives of Dermatology” This case study discusses a patient with persistent 20-nail dystrophy following alopecia areata, suggesting that "20-nail dystrophy" describes a condition with multiple potential causes.
43 citations
,
July 1994 in “Archives of Dermatology” This study found that the prevalence of personality disorders in individuals with androgenetic alopecia was significantly higher than in the general population, irrespective of gender.
43 citations
,
November 1975 in “Archives of Dermatology” This review discusses testosterone metabolism in human skin and its link to androgenetic alopecia, acne vulgaris, and idiopathic hirsutism, but it presents no new results.
42 citations
,
August 1972 in “Archives of Disease in Childhood” This study observed that infants exposed to diazoxide in utero exhibited abnormal hair growth and, in some cases, impaired glucose tolerance, particularly those born to diabetic mothers.
41 citations
,
February 1970 in “Archives of Dermatology” This review discusses various cutaneous side effects potentially linked to oral contraceptive use but provides no new clinical results, emphasizing the need for more evidence in certain associations.
40 citations
,
August 2010 in “Archives of dermatology” This case report describes the youngest known patient with viral-associated trichodysplasia of immunosuppression, where systemic valganciclovir therapy improved facial papule eruptions following cardiac transplantation.