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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Noggin is necessary to start the hair growth phase in skin after birth.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Zinc is effective for treating various skin conditions, including warts and acne.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Accurate diagnosis and effective oral treatment are key to managing tinea capitis and preventing its spread.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

PLD is an effective and safer alternative for treating breast cancer.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.