research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
Search
for
Sort by
Research
270-300 / 1000+ results 
research High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
research Shorter CAG Repeats in the Androgen Receptor Gene May Enhance Hyperandrogenicity in Polycystic Ovary Syndrome
Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.
research Frontal Fibrosing Alopecia
Frontal fibrosing alopecia causes hairline recession and eyebrow loss in postmenopausal women.
research How Effective Is Finasteride Treatment Against Hereditary Male Pattern Baldness
Finasteride treatment slows down hair loss, boosts hair growth, and may increase hair thickness or length, but it can cause side effects like decreased libido and depression in less than 1% of people.
research Frontal Fibrosing Alopecia: Study of 12 Cases in Argentina
The study found that the average age of women diagnosed with Frontal Fibrosing Alopecia in Argentina is higher than in other countries, but their symptoms are similar.
research Coexistence of Psoriasis and Alopecia Areata with Trachyonychia in a Pediatric Patient with Turner Syndrome
A 6-year-old girl with Turner syndrome also had psoriasis, alopecia areata, and trachyonychia.
research Pathogenesis and Causes of Hirsutism
Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.
research Bicalutamide: A Review
Bicalutamide may help treat female pattern hair loss.
research Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research 46,XY DSD Due to Impaired Androgen Production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research How Does pH Fit in with Oscillating Polar Growth?
pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.
research Androgens Downregulate BMP2, Impairing the Inductive Role of Dermal Papilla Cells on Hair Follicle Stem Cells Differentiation
Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
research Palmoplantar Dyshidrotic Eczema Associated with Secukinumab
A patient got a skin reaction on their hands and feet after using secukinumab for psoriasis.
research Alopecia Areata: Current Situation and Perspectives
Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.
research Analysis of Pediatric Dermatology Inpatient Consultations in a Pediatric Teaching Hospital
Most hospitalized children with skin issues were boys, with allergic skin diseases like atopic dermatitis being most common, and treatments were usually topical.
research Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review
Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
research The Efficacy of Topical Minoxidil 2% Versus Topical Botanically Derived Inhibitors of 5 Alpha Reductase in Treatment of Female Pattern Hair Loss by Trichoscopy
Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.
research Theoretical Evaluation of Twenty Cannabinoid Derivatives on Androgen Receptor or 5α-Reductase Enzyme
Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.
research Efficacy and Safety of Topical KX-826 in Male Subjects with Androgenetic Alopecia: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Study
KX-826 is safe and effectively increases hair count in men with hair loss.
research A Study on the Partial Hair Loss Characteristics and Satisfaction According to Management Behaviors of Hair Loss Patients
Scalp massages and medical treatments for hair loss are more satisfying than folk remedies.
research Lower Prostate Cancer Risk in Swedish Men with the Androgen Receptor E213 A-Allele
Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.
research Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations
Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.
research Vitiligo
Vitiligo causes white skin patches and is linked to autoimmune issues.
research Distribution of Caspase-14 in Epidermis and Hair Follicles Is Evolutionarily Conserved Among Mammals
Caspase-14 is important for skin and hair development in all mammals.
research Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goat Breed
Hexi cashmere goats' hair growth varies by stage, with Hoxc13 linked to hair activity.
research The Clinical Applications of Five-Alpha Reductase Inhibitors
Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Experimental Assessment of 3-Meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-Alpha-Reductase Inhibitors in Silico and in Vivo Models
The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.
research Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.