7 citations,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
43 citations,
February 2013 in “Developmental dynamics” Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.
27 citations,
August 2018 in “Frontiers in Plant Science” High levels of auxin increase root hair growth by activating RSL2 and producing ROS, while high phosphate levels hinder growth by repressing RSL2.
17 citations,
April 2015 in “Tropical Journal of Pharmaceutical Research” Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
March 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Plant root hair growth is controlled by the hormone auxin, which affects the production of certain oxygen-related molecules through a specific process.
April 2021 in “Journal of Investigative Dermatology” Bacteria can help skin regenerate through a process called IL-1β signaling.
Newer retinoid drugs are effective for skin conditions but have significant side effects.
123 citations,
November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
44 citations,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
29 citations,
July 2013 in “The Journal of Sexual Medicine” Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
28 citations,
July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
2 citations,
January 2022 in “Rasayan journal of Chemistry” Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.
124 citations,
September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
111 citations,
October 2008 in “Nature Genetics” Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.
76 citations,
September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
70 citations,
December 2004 in “Differentiation” The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
69 citations,
January 2013 in “Frontiers in Immunology” The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
56 citations,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
56 citations,
September 2013 in “Journal of Biochemistry and Molecular Biology” Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
29 citations,
January 2016 in “Annals of dermatology/Annals of Dermatology” Arachidonic acid helps hair grow by increasing growth factors and improving follicle health.
18 citations,
April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
16 citations,
December 2016 in “Molecular Medicine Reports” Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.
7 citations,
November 2010 in “Genesis” Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
5 citations,
March 2023 in “Archives of dermatological research” Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
4 citations,
December 2020 in “Mammalian genome” Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
3 citations,
October 2022 in “PloS one” Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.