Search

everythinglearnresearchcommunity

for

Search:↓

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

The Ar/miR-221/IGF-1 pathway is involved in male pattern baldness, with miR-221 potentially being a new target for treatment.

Certain genetic variations are linked to hair loss in Mexican men.

Mutations in the AR gene cause hair thinning and loss.

Gene differences affect finasteride side effects in men with hair loss.

Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

Phenylephrine may help prevent hair loss from pulling on the hair roots.

Finasteride treatment slows down hair loss, boosts hair growth, and may increase hair thickness or length, but it can cause side effects like decreased libido and depression in less than 1% of people.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Reduced AR gene methylation may cause early pubic hair growth in girls.

G allele of AR Stul polymorphism linked to higher hair loss risk, especially in white people.

AR gene not major factor in female hair loss; different from male hair loss.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

AI and AR are improving cosmetic dermatology but face challenges like data quality and ethical concerns.

Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Blocking testosterone speeds up wound healing in males.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Androgens can help prevent memory problems caused by apoE4.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.