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Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Finasteride side effects in young men may be linked to specific gene variations.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

A comprehensive approach to educating patients and managing side effects is crucial for improving adherence to multiple sclerosis treatments and patient quality of life.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.