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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Future hair cosmetics will be safer and more effective.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Early hormones shape sex-specific differences in rat glands.

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Tamoxifen caused hair loss in a 52-year-old woman.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.