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The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.

High aldosterone and free testosterone levels link to female hair loss; testing aldosterone may predict hypertension risk.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

A new easy-to-use biosensor was made to detect androgen receptor mRNA, which could help diagnose related conditions quickly.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Clascoterone may be an effective topical treatment for hair loss.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Adenosine complex helps increase hair thickness and density in hair loss.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Thyroid receptor β can help develop new drugs to treat hair loss.

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Androgens may block hair growth signals, targeting this could treat hair loss.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair loss needs more research for better treatments.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.