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Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Caffeine improves hair growth, thickness, and reduces shedding.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

Three siblings with a genetic form of rickets showed different symptoms of the disease.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

Trazodone might help reverse post finasteride syndrome.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Women with PCOS had higher SRAGE levels, possibly linked to BMI, not PCOS.