research Men With Kennedy Disease Have a Reduced Risk of Androgenetic Alopecia
Men with Kennedy disease have less chance of hair loss.
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research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
research Androgenic Alopecia Is Not Useful as an Indicator of Men at High Risk of Prostate Cancer
Baldness at age 40 is not linked to a higher risk of aggressive prostate cancer.
research Minoxidil in the Treatment of Androgenetic Alopecia
Minoxidil helps treat pattern hair loss in both men and women.
research Other Antiandrogens: Alternative Treatments for Acne and Hirsutism
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
research Abiraterone and Spironolactone in Prostate Cancer: A Combination to Avoid
Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
research The Post-Finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
research Circulating and Intraprostatic Sex Steroid Hormonal Profiles in Relation to Male Pattern Baldness and Chest Hair Density Among Men Diagnosed with Localized Prostate Cancers
Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
research COVID-19, Androgens, and Androgenic Alopecia
COVID-19 may worsen with androgens; anti-androgen drugs could help.
research Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor
A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.
research Biotechs Target Stagnant Baldness Market
New drug shows promise for better hair growth in baldness treatment.
research Androgen Excess: A Hallmark of Polycystic Ovary Syndrome
Excess androgens may cause PCOS, not just be a symptom.
research MiR-133a-3p and MiR-145-5p Co-Promote Goat Hair Follicle Stem Cell Differentiation by Regulating NANOG and SOX9 Expression
miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.
research Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells
New compounds may help treat prostate cancer by reducing cell growth.
research Androgens and Cardiovascular Disease
Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Lowering testosterone speeds up wound healing in male mice.
research Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia
Oxidative stress affects hair loss in men with androgenetic alopecia.
research Androgens and Female Sexual Function and Dysfunction—Findings From the Fourth International Consultation of Sexual Medicine
Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research Hair: What Is New in Diagnosis and Management?
Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
research Testosterone Therapy in Women: Myths and Misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
research Hormonal Prevention of Prostate Cancer
Suppressing certain hormones might help prevent prostate cancer.
research Post-Finasteride Syndrome: An Emerging Clinical Problem
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial
Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
research Targets to Treat Androgen Excess in Polycystic Ovary Syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Effects of Topical Application of EGCG on Testosterone-Induced Hair Loss in a Mouse Model
Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.