research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
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research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis
Mice without certain skin proteins had abnormal skin and hair development.
research MicroRNA in Skin Diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Towards a Consensus on How to Diagnose and Quantify Female Pattern Hair Loss – The Female Pattern Hair Loss Severity Index (FPHL-SI)
New method measures female hair loss: Female Pattern Hair Loss Severity Index (FPHL-SI).
research Copy Number Variation Regions in Nellore Cattle: Evidence of Environmental Adaptation
Nellore cattle have genetic variations linked to their adaptation to tropical environments.
research Cognitive and Mood Side Effects of Lower Urinary Tract Medication
Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research Protective Cardiovascular and Renal Actions of Vitamin D and Estrogen
Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Dermal EZH2 Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development
Dermal EZH2 controls skin cell development and hair growth in mice.
research Differential Impact of Environmental Factors on Systemic and Localized Autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
research New Insights Into Inflammatory Memory of Epidermal Stem Cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
research Distinct Mechanisms for Sebaceous Gland Self-Renewal and Regeneration Provide Durability in Response to Injury
Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
research Tea and Tea Product Diversification: A Review
Diversifying tea products can boost profits and meet global market demands.
research Association of DNA Damage with Vitamin D and Hair Heavy Metals in Obese Women
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Forensic and Legal Medicine
Forensic medicine is crucial for justice and needs continuous innovation and technology integration.
research Current Issues on the Genetic Implications and Treatment of Androgenic Alopecia
Hair loss is linked to heart disease and metabolic syndrome, and while current treatments vary in effectiveness, more research is needed for better solutions.
research Translational Research in the Generation of Therapeutic Medicine for Wound Healing: A Review
New therapies show promise for wound healing, but more research is needed for safe, affordable options.
research Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in the Mouse
Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.
research Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in Mice
Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.
research Vitamin D in Dermatology and Cosmetology
Vitamin D is crucial for skin health and managing skin diseases.
research Worldwide Cancer Incidences Analyzed by Sex, Age, and Skin Type Over Time (1955-2007), Excluding Skin Cancer, Reveals Important Carcinogenic Drivers
Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.
research Peer Review of Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, and Cuticle Analysis
The research found that people's hair proteins vary, especially by ethnicity and body part, which could help identify individuals in forensic science.