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This study concluded that cyproterone acetate alone produced antiandrogenic effects on the female gerbil prostate, while ethinyloestradiol alone stimulated estrogenic activity, and their combination led to prostatic lesions.

This review reports on the effects of aging on hair characteristics such as pigmentation, growth, and structural properties across genders and ethnicities, highlighting the importance of scalp health and suggesting cosmetic solutions to improve the appearance of aged hair.

This study found that women with PCOS had significantly higher hair cortisol concentrations, suggesting hyperactivation of the HPA axis may affect metabolic and inflammatory markers in those with elevated cortisol levels.

This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.

This article discusses the role of the androgen receptor in regulating development and homeostasis, and reviews treatment approaches for conditions related to hormone imbalances, without reporting new clinical findings.

This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.

This study characterized the SARM PF-05314882, finding it demonstrates anabolic activity in rats with minimal effects on the prostate, seminal vesicles, and luteinizing hormone levels.

This study found that various steroids affected the mRNA expression of enzymes involved in lipid metabolism in hamster flank organs, with different impacts depending on the steroid and combination used.

Lactiplantibacillus plantarum ZJUIDS51 can help regrow hair and improve scalp health in androgenic alopecia.

This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.

In this study of 131 healthy men aged 30 to 45, no relationship was found between androgen receptor gene polymorphisms related to androgen sensitivity and biological age markers, suggesting that other factors may influence the aging process independently of these genetic variations.

This study highlights how the COVID-19 pandemic has exacerbated stress-related dermatological issues like acne and hair loss by affecting skin and hair cycles through stress hormones, emphasizing the need for comprehensive psychoneuroendocrine-informed approaches to diagnosis and treatment.

This study found that among young women in West Bengal, India, co-occurring PCOS and related conditions like estrogen resistance and leptin receptor insufficiency are common, with notable genetic variations identified, including impairments in leptin signaling and insulin resistance.

In this study, researchers examined androgen receptor activity in the adult mouse brain and found specific expression in key brain areas, which could inform understanding of cognitive side effects in humans undergoing androgen deprivation therapy for prostate cancer.

This study outlines a multidisciplinary approach to investigate primary amenorrhea, emphasizing the necessity to consider medical history, physical examination, and potential hormonal or anatomical causes, and recommends early referral in cases of chromosomal abnormalities or persistent amenorrhea following the development of secondary sexual characteristics.

This article reviews the use of hair cortisol concentration as a biomarker to assess long-term stress in both animals and humans, but it reports no new experimental results.

This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.

This study found that Oncostatin M, via JAK-STAT5 signaling, keeps hair follicle stem cells inactive, and its removal leads to hair growth initiation in mice.

In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.

This review discusses the types, causes, and treatments for skin pigmentation disorders, examining clinically tested options including 25 plants, four marine species, and 17 medications.

This review reports no new results but highlights the secretory function of keratinocytes, focusing on how various secretions, notably growth factors, impact stem cell differentiation into keratinocytes.

This study used a probabilistic Boolean network model to explore hair follicle cell fate regulation and predicted that varying TGF-β levels, in coordination with BMP and TNF, can influence either apoptosis or cell proliferation during different follicle growth stages.

In this study, clinically used preoperative skin preparations with povidone iodine and chlorhexidine gluconate did not meet FDA log-reduction standards for bacterial bioburden in a porcine model, suggesting persistent infection risks.

This review discusses various types of stem cells used in regenerative medicine, including adult stem cells and induced pluripotent stem cells (iPSCs), and evaluates them based on their embryonic tissue origins to explore new therapeutic approaches.

In this review, the potential role of the hormone prolactin in skin biology and its implications for treating skin diseases and hair disorders are explored, with a focus on its stress-related impacts and possible immunomodulatory function in the context of COVID-19.

This study provides a detailed overview of 1,295 clinical trials related to alcohol dependence registered on ClinicalTrials.gov, highlighting that 59.15% of these trials have been completed, primarily as interventional studies, with most located in North America.

This study identified a new genetic variant in the KRT71 gene responsible for a breed-specific form of hypotrichosis in Hereford cattle, potentially serving as a model for similar human conditions.

In this study, researchers developed a nanocomposite microneedle patch containing copper/zinc dual-doped silica nanoparticles, which release substances to promote hair follicle regeneration by targeting various pathophysiological aspects of androgenic alopecia, presenting an effective anti-hair loss treatment strategy.

In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.

This study introduces a novel holistic treatment approach for keloid that combines systemic therapies, including Traditional Chinese Medicine, with local interventions to target the inflammatory microenvironment and keloid predisposition for improved management and prevention of recurrence.