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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Lowering testosterone speeds up wound healing in male mice.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.

Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

UV-B light increases inflammation-related substances in acne-related skin cells.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Gintonin-enriched fraction promotes hair growth and could be a potential alopecia treatment.

COVID-19 may worsen with androgens; anti-androgen drugs could help.

Topical cetirizine 1% promotes hair growth in male androgenetic alopecia patients.

Eastern Red Bat hair contains various glycerophospholipids, mainly phosphatidylcholine.