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Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Men with early-onset baldness have a higher chance of heart disease and clogged arteries.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Hair loss from genetics and hormones can be treated with drugs or surgery.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Hormonal antiandrogen therapy for acne is underused and can reduce the need for antibiotics.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Nurses are crucial in managing chemotherapy side effects for ovarian cancer patients to improve their quality of life.

Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Methyl vanillate spray increases hair count and hair mass in women with hair loss.

Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.