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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair loss needs more research for better treatments.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Lowering testosterone speeds up wound healing in male mice.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

New treatments for male hypogonadism are effective and should be personalized.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.

Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.