May 2025 in “The Journal of Rheumatology” This case report highlights the rare occurrence of overlapping syndromes including SLE, RA, and AAV in a patient with discoid lupus erythematosus, noting the persistent role of prior viral infection remains unclear.
May 2025 in “The Journal of Rheumatology” In this case report, researchers detailed the clinical management and positive outcome of a 62-year-old woman with catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus, highlighting the potential effectiveness of Eculizumab in achieving disease remission and maintaining stability over 18 months.
May 2025 in “The Journal of Rheumatology” This case report highlights the importance of trans-esophageal echocardiography in distinguishing Libman-Sacks endocarditis from infective endocarditis in systemic lupus erythematosus patients, guiding appropriate treatment for associated cerebrovascular disease.
May 2025 in “The Journal of Rheumatology” This report describes two cases where female patients with chronic granulomatous disease developed manifestations of systemic lupus erythematosus, highlighting a rare association that may influence clinical evaluation and treatment planning.
May 2025 in “The Journal of Rheumatology” In this case report, two patients with polyautoimmunity and difficult-to-treat lupus erythematosus experienced significant symptom improvement after adding anifrolumab to their regimen, suggesting its potential as an effective add-on therapy for refractory cutaneous symptoms in autoimmune conditions characterized by elevated interferon alpha activity.
May 2025 in “The Journal of Rheumatology” This case report suggests that a proactive physical therapy model can be effective for improving physical function and meeting exercise guidelines in patients newly diagnosed with systemic lupus erythematosus.
May 2025 in “The Journal of Rheumatology” This case report describes a 32-year-old Filipino female with mixed connective tissue disease who sequentially developed distinct autoimmune disorders over seven years, highlighting the complexities in diagnosis and management of overlap syndromes.
May 2025 in “The Journal of Rheumatology” In this case report, two patients with coexisting systemic lupus erythematous and neuromyelitis optica spectrum disorder achieved remission of SLE activity using an anti-CD19 monoclonal antibody.
May 2025 in “The Journal of Rheumatology” This case report describes a young female with pediatric SLE and latent TB who was found to have gastrointestinal tuberculosis, a rarely recognized and often misdiagnosed condition, highlighting the diagnostic challenges and need for early recognition in such cases.
May 2025 in “The Journal of Rheumatology” This case report describes a 21-year-old woman whose catatonia led to the diagnosis of systemic lupus erythematosus, suggesting catatonia may be an underrecognized manifestation of neuropsychiatric lupus.
May 2025 in “The Journal of Rheumatology” This case report details a 56-year-old woman's diagnosis with an overlapping syndrome of dermatomyositis, systemic lupus, and secondary antiphospholipid syndrome, highlighted by purpura fulminans, treated successfully with immunosuppressants and plasmapheresis.
May 2025 in “The Journal of Rheumatology” This study highlights the efforts of the Oyemam Autoimmune Foundation in raising awareness and supporting lupus patients in Ghana, amid challenges like misdiagnosis and insufficient healthcare resources, revealing the impact of their advocacy and counseling initiatives on patients' lives.
May 2025 in “The Journal of Rheumatology” In this case report, researchers describe a rare instance of bullous lupus presenting with severe esophageal involvement in a 42-year-old woman, highlighting the significant diagnostic and therapeutic challenges encountered in such cases despite successful treatment with immunosuppressive therapy.
May 2025 in “The Journal of Rheumatology” This case report describes a patient with systemic lupus erythematosus whose unusual nephrological presentation led to a diagnosis of C3 glomerulopathy, highlighting the importance of considering atypical findings to broaden diagnostic approaches.
May 2025 in “The Journal of Rheumatology” In this case report, a 64-year-old woman diagnosed with both NMOSD and SLE showed mild improvement in vision and recovered from thrombocytopenia after treatment with glucocorticoids and Rituximab, highlighting the importance of accurate diagnosis and tailored treatment for overlapping autoimmune disorders.
May 2025 in “The Journal of Rheumatology” This case report describes a woman whose initial presentation of SLE was persistent watery diarrhea, diagnosed as lymphocytic enterocolitis, and shows that immunosuppressive therapy resulted in symptom relief.
1160 citations
,
November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
38 citations
,
January 2014 in “International Journal of Endocrinology” This review highlights that children with adrenal disorders may experience neurological and psychiatric symptoms, with potential long-term cognitive and behavioral effects from excess glucocorticoids.
26 citations
,
June 2018 in “The journal of immunology/The Journal of immunology” This study demonstrated that AIRE-deficient rats exhibit key symptoms of APECED, making them a relevant model for exploring potential treatments.
25 citations
,
February 2014 in “British journal of dermatology/British journal of dermatology, Supplement” The authors concluded that intralesional triamcinolone acetonide may benefit patients with patch-type alopecia areata, but the evidence is limited due to small, bias-prone studies with variations in treatment protocols.
23 citations
,
March 2001 in “Clinics in dermatology” This study found that 363 genes were differentially expressed in alopecia areata skin compared to non-lesional skin, suggesting T-cell mediated immune responses and distinct gene profiles related to the disease's stage.
12 citations
,
May 2017 in “Pharmacology & therapeutics” This review discusses the mechanisms underlying immune tolerance failure in alopecia areata and highlights potential therapeutic avenues for restoring hair growth and achieving sustained remission, but reports no new clinical results.
11 citations
,
July 2012 in “Current Opinion in Pediatrics” This review discusses dermatologic signs in childhood endocrine disorders and highlights their importance in early diagnosis and treatment, but it reports no new clinical findings.
10 citations
,
May 2020 in “Dermatology Research and Practice” This review discusses "follicular hypoglycania" as a potential pathology in hair growth disorders and reports that proteoglycan replacement therapy may improve hair loss treatments, though it presents no new clinical trial results.
7 citations
,
February 2018 in “InTech eBooks” This article reviews how biomaterials and stem cells could advance regenerative medicine but does not report new results, emphasizing the potential of combining novel biomaterials with stem cells for effective therapies.
5 citations
,
February 2022 in “Frontiers in physiology” This review discusses the role of various cells outside the hair follicle in regulating melanocyte stem cells and hair graying, but reports no new clinical results.
3 citations
,
February 2014 in “Asian Pacific journal of tropical medicine” This study observed that Wnt5a mRNA expression in mice correlates with the hair cycle and inhibits hair follicle growth by antagonizing the Wnts pathway.
January 2024 in “Journal of neurogastroenterology and motility” This study found that gQlab probiotics improved overall IBS symptoms, particularly in female and constipation-predominant patients, compared to placebo after 4 weeks of treatment.
This study developed a new analytical method to identify a wide range of endocrine disrupting compounds in full-term amniotic fluid, revealing diverse substances with potential endocrine activity.
December 2018 in “Neuroradiology” MRI helps distinguish between pituitary adenomas and craniopharyngiomas, guides treatment for pediatric CNS tumors, and assesses rhinocerebral mucormycosis with a high mortality rate in transplanted patients.