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The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Polymeric nanoparticles show promise for treating skin diseases.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

The Rotterdam Study aims to understand various diseases in older adults.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

PGD2 stops hair growth and is higher in bald men with AGA.

Lactate production is important for activating hair growth stem cells.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Fungi-produced compounds can change plant root growth.

Dermatologists need to understand hair products to treat hair and scalp issues better.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.